U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gcna germ cell nuclear acidic peptidase [ Danio rerio (zebrafish) ]

Gene ID: 541448, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
gcnaprovided by ZNC
Official Full Name
germ cell nuclear acidic peptidaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050320-153
See related
Ensembl:ENSDARG00000101060 AllianceGenome:ZFIN:ZDB-GENE-050320-153
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
acrc; zgc:113346
Summary
Acts upstream of or within mitotic nuclear division and regulation of chromosome segregation. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 4. Orthologous to human GCNA (germ cell nuclear acidic peptidase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See gcna in Genome Data Viewer
Location:
chromosome: 14
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (14667274..14687020, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (14361711..14381441, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene NAD(P) dependent steroid dehydrogenase-like Neighboring gene centrin, EF-hand protein, 2 Neighboring gene O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2 Neighboring gene O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Mechanism of toxic effects of Nano-ZnO on cell cycle of zebrafish (Danio rerio). Hou J, et al. Chemosphere, 2019 Aug. PMID 31078877
  2. GCNA Preserves Genome Integrity and Fertility Across Species. Bhargava V, et al. Dev Cell, 2020 Jan 6. PMID 31839537, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within mitotic nuclear division IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of chromosome segregation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to stress IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
germ cell nuclear acidic protein
Names
acidic repeat containing
acidic repeat-containing protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013573.1 → NP_001013591.1  germ cell nuclear acidic protein

    See identical proteins and their annotated locations for NP_001013591.1

    Status: PROVISIONAL

    Source sequence(s)
    BC090463
    UniProtKB/TrEMBL
    Q5BLF3
    Related
    ENSDARP00000141634.1, ENSDART00000169970.2
    Conserved Domains (1) summary
    pfam10263
    Location:384 → 535
    SprT-like; SprT-like family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    14667274..14687020 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481016.2 → XP_021336691.1  germ cell nuclear acidic protein isoform X1

    UniProtKB/Swiss-Prot
    A0A0R4IWG9
    UniProtKB/TrEMBL
    A0A8M9QKK8
    Conserved Domains (2) summary
    pfam10263
    Location:383 → 535
    SprT-like; SprT-like family
    cl27000
    Location:22 → 274
    TFIIFa; Transcription initiation factor IIF, alpha subunit, N-terminal region of RAP74. Subunit of transcription initiation complex involved in initiation, elongation and promoter escape.Tetramer of 2 alpha and 2 beta TFIIF subunits interacts directly with RNA ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0R4IWG9.1 GenPept UniProtKB/Swiss-Prot:A0A0R4IWG9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools