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plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 [ Danio rerio (zebrafish) ]

Gene ID: 541487, updated on 2-Nov-2024

Summary

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Official Symbol
plcxd3provided by ZNC
Official Full Name
phosphatidylinositol-specific phospholipase C, X domain containing 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-050327-10
See related
Ensembl:ENSDARG00000054794 AllianceGenome:ZFIN:ZDB-GENE-050327-10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc10h08; wu:fc10h08; wu:fq34d10; zgc:110845; wu:cegs2770
Summary
Predicted to enable phosphoric diester hydrolase activity. Predicted to act upstream of or within lipid catabolic process and signal transduction. Predicted to be active in synapse. Is expressed in basal plate midbrain region; central nervous system; neurons; otic vesicle; and pharyngeal arch. Orthologous to human PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See plcxd3 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (31821441..31862843)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (31812209..31853611)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene rab7a interacting mon1-ccz1 complex subunit 1 Neighboring gene 3-oxoacid CoA transferase 1a Neighboring gene complement component 7a Neighboring gene regulator of G protein signaling 7 binding protein a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of receptors for growth hormone and somatolactin in fish and land vertebrates: lessons from the lungfish and sturgeon orthologues. Fukamachi S, et al. J Mol Evol, 2007 Oct. PMID 17917757
  2. Identification of enhancer regulatory elements that direct epicardial gene expression during zebrafish heart regeneration. Cao Y, et al. Development, 2022 Feb 15. PMID 35179181, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphoric diester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphoric diester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within lipid catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
PI-PLC X domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014300.1 → NP_001014322.1  PI-PLC X domain-containing protein 3

    See identical proteins and their annotated locations for NP_001014322.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091866
    UniProtKB/Swiss-Prot
    Q58EK3
    UniProtKB/TrEMBL
    A8KC50
    Related
    ENSDARP00000071521.4, ENSDART00000077053.5
    Conserved Domains (1) summary
    cd08616
    Location:19 → 311
    PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    31821441..31862843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q58EK3.1 GenPept UniProtKB/Swiss-Prot:Q58EK3

Gene LinkOut

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