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ZFAND6 zinc finger AN1-type containing 6 [ Homo sapiens (human) ]

Gene ID: 54469, updated on 27-Nov-2024

Summary

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Official Symbol
ZFAND6provided by HGNC
Official Full Name
zinc finger AN1-type containing 6provided by HGNC
Primary source
HGNC:HGNC:30164
See related
Ensembl:ENSG00000086666 MIM:610183; AllianceGenome:HGNC:30164
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AWP1; ZA20D3; ZFAND5B
Summary
Predicted to enable polyubiquitin modification-dependent protein binding activity. Involved in cellular response to tumor necrosis factor; negative regulation of apoptotic process; and regulation of canonical NF-kappaB signal transduction. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis (RPKM 50.8), thyroid (RPKM 41.4) and 25 other tissues See more
Orthologs
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Genomic context

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See ZFAND6 in Genome Data Viewer
Location:
15q25.1
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (80058951..80138393)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (77923092..78001808)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (80352018..80430735)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9937 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr15:80262962-80264161 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9938 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9939 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9940 Neighboring gene ribonucleotide reductase regulatory subunit M2 pseudogene Neighboring gene BCL2 related protein A1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:80293949-80294721 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr15:80295257-80296456 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_41344 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9941 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9942 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:80320394-80320775 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:80324347-80325092 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:80325837-80326580 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:80325093-80325836 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:80332051-80332550 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:80351696-80352024 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9943 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:80404705-80405431 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6731 Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr15:80452567-80453210 and GRCh37_chr15:80453211-80453853 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:80460174-80460674 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:80478509-80479009 Neighboring gene fumarylacetoacetate hydrolase Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_41453 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_41475 Neighboring gene cortexin domain containing 1 Neighboring gene NANOG hESC enhancer GRCh37_chr15:80534358-80534901

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. [Construction of GFP-AWP1 fusion gene vector and its expression in 293 cells]. Cao YK, et al. Di Yi Jun Yi Da Xue Xue Bao, 2005 Feb. PMID 15698998
  2. Measurement of binding strength between prey proteins interacting with Toxoplasma gondii SAG1 and SAG2 using isothermal titration calorimetry (ITC). Lai MY, et al. Acta Parasitol, 2018 Mar 26. PMID 29351065
  3. Genetic associations of TMEM154, PRC1 and ZFAND6 loci with type 2 diabetes in an endogamous business community of North India. Walia GK, et al. PLoS One, 2023. PMID 37738238, Free PMC Article
  4. EIF4A3-induced circZFAND6 promotes breast cancer proliferation and metastasis through the miR-647/FASN axis. Huang X, et al. Life Sci, 2023 Jul 1. PMID 37127184
  5. AWP1 binds to tumor necrosis factor receptor-associated factor 2 (TRAF2) and is involved in TRAF2-mediated nuclear factor-kappaB signaling. Chang EJ, et al. Int J Biochem Cell Biol, 2011 Nov. PMID 21810480

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Genetic associations of TMEM154, PRC1 and ZFAND6 loci with type 2 diabetes in an endogamous business community of North India.
    Title: Genetic associations of TMEM154, PRC1 and ZFAND6 loci with type 2 diabetes in an endogamous business community of North India.
  2. EIF4A3-induced circZFAND6 promotes breast cancer proliferation and metastasis through the miR-647/FASN axis.
    Title: EIF4A3-induced circZFAND6 promotes breast cancer proliferation and metastasis through the miR-647/FASN axis.
  3. Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population.
    Title: Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population.
  4. ZFAND6 was identified as a type 2 diabetes susceptibility gene. ZFAND6 plays a role in insulin secretion in vitro.
    Title: Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion.
  5. By observing the data obtained from the isothermal titration calorimetry assay, both of the human proteins (KRCC1 and ZFAND6) were demonstrated to bind to their respective Toxoplasma gondii SAG1 and SAG2 proteins.
    Title: Measurement of binding strength between prey proteins interacting with Toxoplasma gondii SAG1 and SAG2 using isothermal titration calorimetry (ITC).
  6. The AN1 domain of AWP1 mediated the functional interaction with tumor necrosis factor receptor-associated factor 2, and the A20 domain was responsible for the negative regulation of nuclear factor kappaB activation.
    Title: AWP1 binds to tumor necrosis factor receptor-associated factor 2 (TRAF2) and is involved in TRAF2-mediated nuclear factor-kappaB signaling.
  7. Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
    Title: Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.
  8. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
    Title: Genome-wide searching of rare genetic variants in WTCCC data.
  9. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables polyubiquitin modification-dependent protein binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
  
involved_in cellular response to tumor necrosis factor IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein targeting to peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein targeting to peroxisome ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of canonical NF-kappaB signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
AN1-type zinc finger protein 6
Names
protein associated with PRK1
zinc finger, A20 domain containing 3
zinc finger, AN1-type domain 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242911.2 → NP_001229840.1  AN1-type zinc finger protein 6 isoform a

    See identical proteins and their annotated locations for NP_001229840.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode isoform a.
    Source sequence(s)
    AC092701, AL136598, AW571396, DB050060
    Consensus CDS
    CCDS10313.1
    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Related
    ENSP00000454137.1, ENST00000558494.5
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  2. NM_001242912.2 → NP_001229841.1  AN1-type zinc finger protein 6 isoform a

    See identical proteins and their annotated locations for NP_001229841.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode isoform a.
    Source sequence(s)
    AC092701, AW571396, BX363429, DB050060
    Consensus CDS
    CCDS10313.1
    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Related
    ENSP00000479071.1, ENST00000613266.4
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  3. NM_001242913.2 → NP_001229842.1  AN1-type zinc finger protein 6 isoform a

    See identical proteins and their annotated locations for NP_001229842.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode isoform a.
    Source sequence(s)
    AC092701, AW571396, CN428457
    Consensus CDS
    CCDS10313.1
    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Related
    ENSP00000478129.1, ENST00000616533.4
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  4. NM_001242914.2 → NP_001229843.1  AN1-type zinc finger protein 6 isoform a

    See identical proteins and their annotated locations for NP_001229843.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode isoform a.
    Source sequence(s)
    AC092701, AW571396, BG720174, BI562073
    Consensus CDS
    CCDS10313.1
    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Related
    ENSP00000484971.1, ENST00000618205.4
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  5. NM_001242915.2 → NP_001229844.1  AN1-type zinc finger protein 6 isoform a

    See identical proteins and their annotated locations for NP_001229844.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode isoform a.
    Source sequence(s)
    AF261138, AW571396, DA091136
    Consensus CDS
    CCDS10313.1
    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Related
    ENSP00000453291.1, ENST00000559835.5
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  6. NM_001242916.2 → NP_001229845.1  AN1-type zinc finger protein 6 isoform a

    See identical proteins and their annotated locations for NP_001229845.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode isoform a.
    Source sequence(s)
    AC092701, AW571396, DA091136, DR762914
    Consensus CDS
    CCDS10313.1
    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Related
    ENSP00000453709.1, ENST00000559775.5
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  7. NM_001242917.2 → NP_001229846.1  AN1-type zinc finger protein 6 isoform b

    See identical proteins and their annotated locations for NP_001229846.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a.
    Source sequence(s)
    AC092701, AF061739, AW571396, DB050060
    Consensus CDS
    CCDS58395.1
    UniProtKB/TrEMBL
    B2R6N3
    Related
    ENSP00000454152.1, ENST00000559157.6
    Conserved Domains (3) summary
    smart00154
    Location:137 → 174
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 35
    zf-A20; A20-like zinc finger
    pfam06484
    Location:25 → 130
    Ten_N; Teneurin Intracellular Region

  8. NM_001242918.2 → NP_001229847.1  AN1-type zinc finger protein 6 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a.
    Source sequence(s)
    AC092701, AW571396, BP231220, DB050060
    UniProtKB/TrEMBL
    H3BM82
    Related
    ENSP00000454273.1, ENST00000564367.5
    Conserved Domains (3) summary
    pfam01754
    Location:12 → 35
    zf-A20; A20-like zinc finger
    pfam06484
    Location:25 → 117
    Ten_N; Teneurin Intracellular Region
    cl01438
    Location:118 → 148
    zf-AN1; AN1-like Zinc finger

  9. NM_001242919.1 → NP_001229848.1  AN1-type zinc finger protein 6 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR and uses two alternate in-frame splice sites in the central coding region, compared to variant 1. The encoded isoform (d) is shorter than isoform a.
    Source sequence(s)
    AC092701, AW571396, BP234517
    UniProtKB/TrEMBL
    B2R6N3
    Conserved Domains (2) summary
    smart00154
    Location:122 → 159
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 35
    zf-A20; A20-like zinc finger

  10. NM_019006.4 → NP_061879.2  AN1-type zinc finger protein 6 isoform a

    See identical proteins and their annotated locations for NP_061879.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1-7 all encode isoform a.
    Source sequence(s)
    AW571396, BC005283, DB050060
    Consensus CDS
    CCDS10313.1
    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Related
    ENSP00000261749.6, ENST00000261749.11
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    80058951..80138393
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047432697.1 → XP_047288653.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3

  2. XM_024449959.2 → XP_024305727.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  3. XM_024449956.2 → XP_024305724.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  4. XM_024449963.2 → XP_024305731.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  5. XM_047432696.1 → XP_047288652.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3

  6. XM_047432695.1 → XP_047288651.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3

  7. XM_011521684.3 → XP_011519986.1  AN1-type zinc finger protein 6 isoform X1

    See identical proteins and their annotated locations for XP_011519986.1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
    UniProtKB/TrEMBL
    B2R6N3
    Conserved Domains (2) summary
    smart00154
    Location:149 → 186
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

  8. XM_047432694.1 → XP_047288650.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    77923092..78001808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054378223.1 → XP_054234198.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3

  2. XM_054378226.1 → XP_054234201.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3

  3. XM_054378225.1 → XP_054234200.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3

  4. XM_054378224.1 → XP_054234199.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3

  5. XM_054378222.1 → XP_054234197.1  AN1-type zinc finger protein 6 isoform X1

    UniProtKB/Swiss-Prot
    D3DW92, D3DW94, O95792, Q6FIF0, Q9BQF7, Q9GZY3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6FIF0.2 GenPept UniProtKB/Swiss-Prot:Q6FIF0

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