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Catspere2 cation channel sperm associated auxiliary subunit epsilon 2 [ Mus musculus (house mouse) ]

Gene ID: 545391, updated on 9-Dec-2024

Summary

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Official Symbol
Catspere2provided by MGI
Official Full Name
cation channel sperm associated auxiliary subunit epsilon 2provided by MGI
Primary source
MGI:MGI:5589632
See related
Ensembl:ENSMUSG00000091476 AllianceGenome:MGI:5589632
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm16432; Gm30473
Summary
Predicted to be involved in flagellated sperm motility and sperm capacitation. Predicted to be part of CatSper complex. Predicted to be active in sperm principal piece. Orthologous to human CATSPERE (catsper channel auxiliary subunit epsilon). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in testis adult (RPKM 4.8), adrenal adult (RPKM 0.6) and 3 other tissues See more
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Genomic context

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See Catspere2 in Genome Data Viewer
Location:
1 H4; 1 82.87 cM
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (177810724..178000273)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (177983155..178172707)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4395 Neighboring gene STARR-positive B cell enhancer ABC_E632 Neighboring gene STARR-seq mESC enhancer starr_03135 Neighboring gene adenylosuccinate synthase 2 Neighboring gene ribosomal protein S8 pseudogene Neighboring gene cation channel sperm associated auxiliary subunit epsilon 1 Neighboring gene STARR-seq mESC enhancer starr_03137 Neighboring gene STARR-positive B cell enhancer ABC_E2589 Neighboring gene predicted gene, 25312 Neighboring gene STARR-seq mESC enhancer starr_03139 Neighboring gene STARR-positive B cell enhancer ABC_E4396 Neighboring gene translin-associated factor X pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr1:180115890-180116191 Neighboring gene STARR-positive B cell enhancer ABC_E2023 Neighboring gene desumoylating isopeptidase 2 Neighboring gene STARR-seq mESC enhancer starr_03140 Neighboring gene STARR-positive B cell enhancer mm9_chr1:180172365-180172665 Neighboring gene predicted gene 8023

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in flagellated sperm motility IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sperm capacitation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of CatSper complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of CatSper complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in sperm principal piece IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in sperm principal piece ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
cation channel sperm-associated protein subunit epsilon-like protein
Names
catSper-epsilon-like
catSperepsilon-like
catsper channel auxiliary subunit epsilon 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034899.3 → NP_001030071.2  cation channel sperm-associated protein subunit epsilon-like protein isoform b precursor

    See identical proteins and their annotated locations for NP_001030071.2

    Status: VALIDATED

    Source sequence(s)
    AK131684, BC147686
    Consensus CDS
    CCDS35802.1
    UniProtKB/TrEMBL
    A0A5F8MPD0
    Related
    ENSMUSP00000091828.5, ENSMUST00000094273.10

  2. NM_001368822.1 → NP_001355751.1  cation channel sperm-associated protein subunit epsilon-like protein isoform a precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) encodes the longer isoform (a).
    Source sequence(s)
    AC113044, AC119928, AC124621
    Consensus CDS
    CCDS87931.1
    UniProtKB/TrEMBL
    A0A571BGH9
    Related
    ENSMUSP00000158854.2, ENSMUST00000238506.2
    Conserved Domains (1) summary
    pfam15020
    Location:729 → 956
    CATSPERD; Cation channel sperm-associated protein subunit delta

RNA

  1. NR_155538.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC119928, AC124621, AK029617, BB616902
    Related
    ENSMUST00000192146.2

  2. NR_160909.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC113044, AC119928, AC124621
    Related
    ENSMUST00000239149.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    177810724..178000273
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030255583.2 → XP_030111443.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X7

    Conserved Domains (1) summary
    pfam15020
    Location:552 → 779
    CATSPERD; Cation channel sperm-associated protein subunit delta

  2. XM_036152449.1 → XP_036008342.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X1

  3. XM_036152450.1 → XP_036008343.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X2

  4. XM_036152451.1 → XP_036008344.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X3

  5. XM_036152454.1 → XP_036008347.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X4

    UniProtKB/Swiss-Prot
    A0A0A6YXX9, B2RW93, Q3V2N6

  6. XM_036152456.1 → XP_036008349.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X5

    UniProtKB/Swiss-Prot
    A0A0A6YXX9, B2RW93, Q3V2N6

  7. XM_036152457.1 → XP_036008350.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X6

    UniProtKB/Swiss-Prot
    A0A0A6YXX9, B2RW93, Q3V2N6

  8. XM_036152458.1 → XP_036008351.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X8

    UniProtKB/Swiss-Prot
    A0A0A6YXX9, B2RW93, Q3V2N6

  9. XM_036152459.1 → XP_036008352.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X8

    UniProtKB/Swiss-Prot
    A0A0A6YXX9, B2RW93, Q3V2N6

  10. XM_036152460.1 → XP_036008353.1  cation channel sperm-associated protein subunit epsilon-like protein isoform X9

RNA

  1. XR_004933815.1 RNA Sequence

  2. XR_004933813.1 RNA Sequence

  3. XR_004933816.1 RNA Sequence

  4. XR_001785174.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0A6YXX9.1 GenPept UniProtKB/Swiss-Prot:A0A0A6YXX9

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