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stard4 StAR related lipid transfer domain containing 4 [ Danio rerio (zebrafish) ]

Gene ID: 550374, updated on 14-Nov-2024

Summary

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Official Symbol
stard4provided by ZNC
Official Full Name
StAR related lipid transfer domain containing 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-168
See related
Ensembl:ENSDARG00000102477 AllianceGenome:ZFIN:ZDB-GENE-050417-168
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:112466
Summary
Predicted to enable cholesterol binding activity and cholesterol transfer activity. Predicted to be involved in cholesterol import; cholesterol transport involved in cholesterol storage; and intracellular cholesterol transport. Predicted to act upstream of or within lipid transport. Predicted to be active in cytosol and endoplasmic reticulum. Orthologous to human STARD4 (StAR related lipid transfer domain containing 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See stard4 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (244518..248613)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (223014..227161)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene nucleoporin 54 Neighboring gene brix domain containing 2 Neighboring gene DTW domain containing 2 Neighboring gene Janus kinase 2a Neighboring gene relaxin 1 Neighboring gene relaxin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cholesterol binding IEA
Inferred from Electronic Annotation
more info
  
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular cholesterol transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
stAR-related lipid transfer protein 4
Names
StAR-related lipid transfer (START) domain containing 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017679.1 → NP_001017679.2  stAR-related lipid transfer protein 4

    See identical proteins and their annotated locations for NP_001017679.2

    Status: PROVISIONAL

    Source sequence(s)
    BC093326
    UniProtKB/TrEMBL
    A0A8M9PTU1, Q566U7
    Related
    ENSDARP00000136540.1, ENSDART00000162889.2
    Conserved Domains (1) summary
    cl14643
    Location:12 → 202
    SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    244518..248613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021468820.2 → XP_021324495.1  stAR-related lipid transfer protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PTU1, Q566U7
    Conserved Domains (1) summary
    cl14643
    Location:12 → 202
    SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily

  2. XM_017352776.3 → XP_017208265.1  stAR-related lipid transfer protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8M6YUG2
    Related
    ENSDART00000169872.2
    Conserved Domains (1) summary
    cl14643
    Location:11 → 162
    SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily
Nucleotide Protein
Heading Accession and Version

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