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SAMD4B sterile alpha motif domain containing 4B [ Homo sapiens (human) ]

Gene ID: 55095, updated on 27-Nov-2024

Summary

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Official Symbol
SAMD4Bprovided by HGNC
Official Full Name
sterile alpha motif domain containing 4Bprovided by HGNC
Primary source
HGNC:HGNC:25492
See related
Ensembl:ENSG00000179134 MIM:619231; AllianceGenome:HGNC:25492
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SMGB; Smaug2
Summary
Enables RNA binding activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within cerebellar neuron development. Located in cytosol. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis (RPKM 7.6), ovary (RPKM 7.3) and 25 other tissues See more
Orthologs
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Genomic context

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See SAMD4B in Genome Data Viewer
Location:
19q13.2
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (39342421..39390764)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (42146695..42195044)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (39833061..39876340)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:39798467-39798968 Neighboring gene leucine rich repeat and fibronectin type III domain containing 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10596 Neighboring gene glia maturation factor gamma Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10597 Neighboring gene RNA, 7SL, cytoplasmic 566, pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr19:39880404-39880535 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14613 Neighboring gene PAF1 homolog, Paf1/RNA polymerase II complex component Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14614 Neighboring gene mediator complex subunit 29 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14615 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:39893943-39894450 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10598 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14616 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:39897901-39898538 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:39898539-39899177 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:39899178-39899815 Neighboring gene ZFP36 ring finger protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. miR‑451 suppresses the malignant characteristics of colorectal cancer via targeting SAMD4B. Wu C, et al. Mol Med Rep, 2021 Aug. PMID 34109425, Free PMC Article
  2. SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity. Luo N, et al. BMB Rep, 2010 May. PMID 20510020
  3. Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules. Baez MV, et al. J Biol Chem, 2005 Dec 30. PMID 16221671
  4. A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. Vizeacoumar FJ, et al. Mol Syst Biol, 2013 Oct 8. PMID 24104479, Free PMC Article
  5. Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. Meek SE, et al. J Biol Chem, 2004 Jul 30. PMID 15161933

See all (48) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. miR451 suppresses the malignant characteristics of colorectal cancer via targeting SAMD4B.
    Title: miR‑451 suppresses the malignant characteristics of colorectal cancer via targeting SAMD4B.
  2. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
    Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
  3. Observational study of gene-disease association. (HuGE Navigator)
    Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
  4. Results suggest that SAMD4B is a widely expressed gene involved in AP-1-, p53-and p21-mediated transcriptional signaling activity.
    Title: SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ10211, MGC99832

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables translation repressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in nuclear-transcribed mRNA poly(A) tail shortening IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein Smaug homolog 2
Names
SAM domain-containing protein 4B
smaug 2
smaug homolog B
sterile alpha motif domain-containing protein 4B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001303614.2 → NP_001290543.1  protein Smaug homolog 2 isoform b

    See identical proteins and their annotated locations for NP_001290543.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and includes an alternate 3' terminal exon, compared to variant 1. The encoded isoform (b) is shorter, and has a distinct C-terminus, compared to isoform a. Variants 2 and 15-19 all encode the same isoform (b).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS77295.1
    UniProtKB/TrEMBL
    M0QZ22, Q66K25
    Related
    ENSP00000470237.1, ENST00000598913.5
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  2. NM_001384565.1 → NP_001371494.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  3. NM_001384566.1 → NP_001371495.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  4. NM_001384568.1 → NP_001371497.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  5. NM_001384569.1 → NP_001371498.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  6. NM_001384570.1 → NP_001371499.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  7. NM_001384571.1 → NP_001371500.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  8. NM_001384573.1 → NP_001371502.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  9. NM_001384574.2 → NP_001371503.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Related
    ENSP00000484229.1, ENST00000610417.5
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  10. NM_001384575.1 → NP_001371504.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  11. NM_001384576.1 → NP_001371505.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  12. NM_001384577.1 → NP_001371506.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  13. NM_001384578.1 → NP_001371507.1  protein Smaug homolog 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (14) differs in the 5' UTR compared to variant 1. Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  14. NM_001384580.1 → NP_001371509.1  protein Smaug homolog 2 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (15) differs in the 5' UTR compared to variant 2. Variants 2 and 15-19 all encode the same isoform (b).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS77295.1
    UniProtKB/TrEMBL
    M0QZ22, Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  15. NM_001384581.1 → NP_001371510.1  protein Smaug homolog 2 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (16) differs in the 5' UTR compared to variant 2. Variants 2 and 15-19 all encode the same isoform (b).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS77295.1
    UniProtKB/TrEMBL
    M0QZ22, Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  16. NM_001384582.1 → NP_001371511.1  protein Smaug homolog 2 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (17) differs in the 5' UTR compared to variant 2. Variants 2 and 15-19 all encode the same isoform (b).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS77295.1
    UniProtKB/TrEMBL
    M0QZ22, Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  17. NM_001384583.1 → NP_001371512.1  protein Smaug homolog 2 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (18) differs in the 5' UTR compared to variant 2. Variants 2 and 15-19 all encode the same isoform (b).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS77295.1
    UniProtKB/TrEMBL
    M0QZ22, Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  18. NM_001384584.1 → NP_001371513.1  protein Smaug homolog 2 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (19) differs in the 5' UTR compared to variant 2. Variants 2 and 15-19 all encode the same isoform (b).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS77295.1
    UniProtKB/TrEMBL
    M0QZ22, Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  19. NM_001384585.1 → NP_001371514.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (20) encodes isoform c.
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  20. NM_001384586.1 → NP_001371515.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (21) differs in the 5' UTR compared to variant 20. Variants 20-29 all encode the same isoform (c).
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  21. NM_001384587.1 → NP_001371516.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (22) differs in the 5' UTR compared to variant 20. Variants 20-29 all encode the same isoform (c).
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  22. NM_001384588.1 → NP_001371517.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (23) differs in the 5' UTR compared to variant 20. Variants 20-29 all encode the same isoform (c).
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  23. NM_001384589.1 → NP_001371518.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (24) differs in the 5' UTR compared to variant 20. Variants 20-29 all encode the same isoform (c).
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  24. NM_001384590.1 → NP_001371519.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (25) differs in the 5' UTR compared to variant 20. Variants 20-29 all encode the same isoform (c).
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  25. NM_001384591.1 → NP_001371520.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (26) differs in the 5' UTR compared to variant 20. Variants 20-29 all encode the same isoform (c).
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  26. NM_001384592.1 → NP_001371521.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (27) differs in the 5' UTR compared to variant 20. Variants 20-29 all encode the same isoform (c).
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  27. NM_001384593.1 → NP_001371522.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (28) differs in the 5' UTR compared to variant 20. Variants 20-29 all encode the same isoform (c).
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  28. NM_001384594.1 → NP_001371523.1  protein Smaug homolog 2 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (29) differs in the 5' UTR compared to variant 20. Variants 20-29 all encode the same isoform (c).
    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  29. NM_001384595.1 → NP_001371524.1  protein Smaug homolog 2 isoform d

    Status: VALIDATED

    Source sequence(s)
    AC005239, AC011445
    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

  30. NM_018028.4 → NP_060498.2  protein Smaug homolog 2 isoform a

    See identical proteins and their annotated locations for NP_060498.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 3-14 all encode the same isoform (a).
    Source sequence(s)
    AC005239, AC011445
    Consensus CDS
    CCDS33020.1
    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194
    UniProtKB/TrEMBL
    Q66K25
    Related
    ENSP00000317224.5, ENST00000314471.10
    Conserved Domains (1) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily

RNA

  1. NR_169271.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC005239, AC011445

  2. NR_169272.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC005239, AC011445

  3. NR_169273.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC005239, AC011445

  4. NR_169274.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC005239, AC011445

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    39342421..39390764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026919.2 → XP_016882408.1  protein Smaug homolog 2 isoform X1

    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (2) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily
    smart00454
    Location:301 → 359
    SAM; Sterile alpha motif

  2. XM_047439027.1 → XP_047294983.1  protein Smaug homolog 2 isoform X1

  3. XM_011527057.3 → XP_011525359.1  protein Smaug homolog 2 isoform X1

    See identical proteins and their annotated locations for XP_011525359.1

    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (2) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily
    smart00454
    Location:301 → 359
    SAM; Sterile alpha motif

  4. XM_011527062.3 → XP_011525364.1  protein Smaug homolog 2 isoform X1

    See identical proteins and their annotated locations for XP_011525364.1

    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (2) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily
    smart00454
    Location:301 → 359
    SAM; Sterile alpha motif

  5. XM_047439028.1 → XP_047294984.1  protein Smaug homolog 2 isoform X1

  6. XM_047439030.1 → XP_047294986.1  protein Smaug homolog 2 isoform X2

    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194

  7. XM_047439031.1 → XP_047294987.1  protein Smaug homolog 2 isoform X2

    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194

  8. XM_047439029.1 → XP_047294985.1  protein Smaug homolog 2 isoform X2

    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194

  9. XM_047439035.1 → XP_047294991.1  protein Smaug homolog 2 isoform X2

    UniProtKB/TrEMBL
    M0QZ22

  10. XM_047439034.1 → XP_047294990.1  protein Smaug homolog 2 isoform X2

    UniProtKB/TrEMBL
    M0QZ22

  11. XM_011527060.4 → XP_011525362.1  protein Smaug homolog 2 isoform X1

    See identical proteins and their annotated locations for XP_011525362.1

    UniProtKB/TrEMBL
    Q66K25
    Conserved Domains (2) summary
    cd09557
    Location:296 → 358
    SAM_Smaug; SAM domain of Smaug subfamily
    smart00454
    Location:301 → 359
    SAM; Sterile alpha motif

  12. XM_047439033.1 → XP_047294989.1  protein Smaug homolog 2 isoform X2

    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194

  13. XM_047439032.1 → XP_047294988.1  protein Smaug homolog 2 isoform X2

    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194

  14. XM_047439036.1 → XP_047294992.1  protein Smaug homolog 2 isoform X2

    UniProtKB/TrEMBL
    M0QZ22

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791808.1 Reference GRCh38.p14 PATCHES

    Range
    122803..137509
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    42146695..42195044
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054321350.1 → XP_054177325.1  protein Smaug homolog 2 isoform X1

  2. XM_054321351.1 → XP_054177326.1  protein Smaug homolog 2 isoform X1

  3. XM_054321349.1 → XP_054177324.1  protein Smaug homolog 2 isoform X1

  4. XM_054321352.1 → XP_054177327.1  protein Smaug homolog 2 isoform X1

  5. XM_054321353.1 → XP_054177328.1  protein Smaug homolog 2 isoform X1

  6. XM_054321355.1 → XP_054177330.1  protein Smaug homolog 2 isoform X2

    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194

  7. XM_054321354.1 → XP_054177329.1  protein Smaug homolog 2 isoform X2

    UniProtKB/Swiss-Prot
    A5Z0M6, Q5PRF9, Q6P194

  8. XM_054321356.1 → XP_054177331.1  protein Smaug homolog 2 isoform X2

    UniProtKB/TrEMBL
    M0QZ22
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5PRF9.1 GenPept UniProtKB/Swiss-Prot:Q5PRF9

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