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lsr lipolysis stimulated lipoprotein receptor [ Danio rerio (zebrafish) ]

Gene ID: 553218, updated on 4-Jan-2025

Summary

Official Symbol
lsrprovided by ZNC
Official Full Name
lipolysis stimulated lipoprotein receptorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050913-73
See related
Ensembl:ENSDARG00000099291 AllianceGenome:ZFIN:ZDB-GENE-050913-73
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
lsrl; Lisch7; zgc:114089
Summary
Acts upstream of or within endoderm development and pancreas development. Predicted to be located in bicellular tight junction and membrane. Predicted to be active in plasma membrane and tricellular tight junction. Is expressed in several structures, including EVL; Kupffer's vesicle; digestive system; pronephros; and sensory system. Orthologous to human LSR (lipolysis stimulated lipoprotein receptor). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See lsr in Genome Data Viewer
Location:
chromosome: 15
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (33939065..33964911, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (34081079..34106950, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene sialic acid-binding Ig-like lectin 14 Neighboring gene myelin associated glycoprotein Neighboring gene transmembrane protein 106Ba Neighboring gene Schwann cell-specific EGF-like repeat autocrine factor

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC114089

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within endoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in establishment of blood-brain barrier IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within pancreas development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in tricellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
 
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in tricellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
lipolysis-stimulated lipoprotein receptor
Names
lsr like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025472.1NP_001020643.1  lipolysis-stimulated lipoprotein receptor precursor

    See identical proteins and their annotated locations for NP_001020643.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097149
    UniProtKB/TrEMBL
    Q4V8Y3
    Related
    ENSDARP00000141082.1, ENSDART00000158126.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    33939065..33964911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005157633.5XP_005157690.1  lipolysis-stimulated lipoprotein receptor isoform X2

    UniProtKB/TrEMBL
    A0A0R4ICU6, A0A8M2B4G9
    Related
    ENSDARP00000130925.1, ENSDART00000160456.2
  2. XM_005157632.5XP_005157689.1  lipolysis-stimulated lipoprotein receptor isoform X1

    UniProtKB/TrEMBL
    A0A8M2B4I8
  3. XM_005157631.5XP_005157688.1  lipolysis-stimulated lipoprotein receptor isoform X3

    UniProtKB/TrEMBL
    A0A0R4IPT5, A0A8M2B3Y8
    Related
    ENSDARP00000136747.3, ENSDART00000163841.3