pisd phosphatidylserine decarboxylase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pisdprovided by ZNC
Official Full Name: phosphatidylserine decarboxylaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-061215-46
See related: Ensembl:ENSDARG00000052462 AllianceGenome:ZFIN:ZDB-GENE-061215-46
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fd05a08; wu:fd05a08; zgc:158135
Summary: Predicted to enable phosphatidylserine decarboxylase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to act upstream of or within phospholipid biosynthetic process. Predicted to be located in lipid droplet and mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human PISD (phosphatidylserine decarboxylase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (57489253..57545043, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (56819036..56874852, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fd05a08.x1 (e-PCR)
- UniSTS:204052

G46981 (e-PCR)
- UniSTS:107775

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables carboxy-lyase activity	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables phosphatidylserine decarboxylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylserine decarboxylase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in phosphatidylethanolamine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphatidylethanolamine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phospholipid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in protein autoprocessing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in lipid droplet	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: phosphatidylserine decarboxylase proenzyme, mitochondrial

NP_001073170.1

EC 4.1.1.65

XP_017211577.1

EC 4.1.1.65

XP_068077283.1

EC 4.1.1.65

XP_068077284.1

EC 4.1.1.65

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001079702.1 → NP_001073170.1 phosphatidylserine decarboxylase proenzyme, mitochondrial

See identical proteins and their annotated locations for NP_001073170.1

Status: PROVISIONAL

Source sequence(s)

BC128795

UniProtKB/TrEMBL

A0A8N1YZL8, A1A5T2

Related

ENSDARP00000016016.8, ENSDART00000022866.10

Conserved Domains (1) summary

cl27394
Location:120 → 424

PLN02964; phosphatidylserine decarboxylase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

57489253..57545043 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017356088.2 → XP_017211577.1 phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A8M6YY80
XM_068221182.1 → XP_068077283.1 phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X2
XM_068221183.1 → XP_068077284.1 phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X3

UniProtKB/TrEMBL

A0A8M9QDX6