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lactb lactamase, beta [ Danio rerio (zebrafish) ]

Gene ID: 553619, updated on 17-Aug-2024

Summary

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Official Symbol
lactbprovided by ZNC
Official Full Name
lactamase, betaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-020111-1
See related
Ensembl:ENSDARG00000040803 AllianceGenome:ZFIN:ZDB-GENE-020111-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:110419
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human LACTB (lactamase beta). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 25
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (33256092..33266382)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (32770665..32780956)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene talin 2b Neighboring gene microRNA 190 Neighboring gene tropomyosin 1 (alpha) Neighboring gene RAR-related orphan receptor A, paralog a Neighboring gene interactor of little elongator complex ELL subunit 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identification, genomic organization, and mRNA expression of LACTB, encoding a serine beta-lactamase-like protein with an amino-terminal transmembrane domain. Smith TS, et al. Genomics, 2001 Nov. PMID 11707067
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC110419

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
serine beta-lactamase-like protein LACTB, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020593.1 → NP_001018429.1  serine beta-lactamase-like protein LACTB, mitochondrial

    See identical proteins and their annotated locations for NP_001018429.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095252
    UniProtKB/TrEMBL
    Q503N1
    Related
    ENSDARP00000059799.3, ENSDART00000059800.4
    Conserved Domains (1) summary
    pfam00144
    Location:109 → 485
    Beta-lactamase; Beta-lactamase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    33256092..33266382
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009298158.3 → XP_009296433.1  serine beta-lactamase-like protein LACTB, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8M3AWR6
    Conserved Domains (1) summary
    pfam00144
    Location:112 → 489
    Beta-lactamase; Beta-lactamase
Nucleotide Protein Strain
Heading Accession and Version

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