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carf calcium responsive transcription factor [ Danio rerio (zebrafish) ]

Gene ID: 555728, updated on 4-Jan-2025

Summary

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Official Symbol
carfprovided by ZNC
Official Full Name
calcium responsive transcription factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070912-172
See related
Ensembl:ENSDARG00000019950 AllianceGenome:ZFIN:ZDB-GENE-070912-172
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
als2cr8; si:ch211-195c14.1
Summary
Predicted to enable DNA-binding transcription factor activity. Orthologous to human CARF (calcium responsive transcription factor). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See carf in Genome Data Viewer
Location:
chromosome: 9
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (13229593..13251327)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (13258368..13280124)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein receptor, type II b (serine/threonine kinase) Neighboring gene uncharacterized LOC103911618 Neighboring gene family with sequence similarity 117 member Bb Neighboring gene KIAA2012 ortholog Neighboring gene frizzled class receptor 7a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
calcium-responsive transcription factor
Names
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    13229593..13251327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478846.2 → XP_021334521.1  calcium-responsive transcription factor isoform X1

    UniProtKB/TrEMBL
    A0A8M9QJZ6
    Conserved Domains (2) summary
    pfam15299
    Location:234 → 485
    ALS2CR8; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8
    cl27427
    Location:552 → 653
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  2. XM_021478848.2 → XP_021334523.1  calcium-responsive transcription factor isoform X2

    UniProtKB/TrEMBL
    A0A8M9PSK7
    Conserved Domains (2) summary
    pfam15299
    Location:230 → 481
    ALS2CR8; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8
    cl27427
    Location:548 → 649
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  3. XM_021478845.2 → XP_021334520.1  calcium-responsive transcription factor isoform X1

    UniProtKB/TrEMBL
    A0A8M9QJZ6
    Conserved Domains (2) summary
    pfam15299
    Location:234 → 485
    ALS2CR8; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8
    cl27427
    Location:552 → 653
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  4. XM_068223558.1 → XP_068079659.1  calcium-responsive transcription factor isoform X3

    UniProtKB/TrEMBL
    A0A8M9QB52, B0UYY8
    Related
    ENSDARP00000118967.2, ENSDART00000141705.4

  5. XM_021478847.2 → XP_021334522.1  calcium-responsive transcription factor isoform X2

    UniProtKB/TrEMBL
    A0A8M9PSK7
    Conserved Domains (2) summary
    pfam15299
    Location:230 → 481
    ALS2CR8; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8
    cl27427
    Location:548 → 649
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  6. XM_068223560.1 → XP_068079661.1  calcium-responsive transcription factor isoform X5

  7. XM_068223559.1 → XP_068079660.1  calcium-responsive transcription factor isoform X4

    UniProtKB/TrEMBL
    A0A8M9QJZ7
    Related
    ENSDARP00000153281.1, ENSDART00000179850.1

RNA

  1. XR_011016793.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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