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ampd3a adenosine monophosphate deaminase 3a [ Danio rerio (zebrafish) ]

Gene ID: 556578, updated on 14-Nov-2024

Summary

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Official Symbol
ampd3aprovided by ZNC
Official Full Name
adenosine monophosphate deaminase 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-110407-2
See related
Ensembl:ENSDARG00000005800 AllianceGenome:ZFIN:ZDB-GENE-110407-2
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkeyp-104h2.1
Summary
Predicted to enable AMP deaminase activity. Predicted to be involved in AMP metabolic process and IMP biosynthetic process. Predicted to act upstream of or within purine ribonucleoside monophosphate biosynthetic process. Predicted to be active in cytosol. Orthologous to human AMPD3 (adenosine monophosphate deaminase 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See ampd3a in Genome Data Viewer
Location:
chromosome: 7
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (66838469..66868450, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (66613900..66644546, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene murine retrovirus integration site 1 homolog Neighboring gene lymphatic vessel endothelial hyaluronic receptor 1a Neighboring gene adrenomedullin a Neighboring gene SET binding factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes. England SJ, et al. Front Cell Dev Biol, 2017. PMID 28271061, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables AMP deaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables deaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within IMP salvage IEA
Inferred from Electronic Annotation
more info
  
involved_in IMP salvage IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within purine ribonucleoside monophosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
AMP deaminase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    66838469..66868450 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009303597.4 → XP_009301872.2  AMP deaminase 3 isoform X1

    Related
    ENSDARP00000124263.1, ENSDART00000149680.3

  2. XM_005169047.5 → XP_005169104.1  AMP deaminase 3 isoform X4

    See identical proteins and their annotated locations for XP_005169104.1

    UniProtKB/TrEMBL
    A0A8M3AUP1
    Conserved Domains (2) summary
    PLN03055
    Location:178 → 745
    PLN03055; AMP deaminase; Provisional
    cl00281
    Location:137 → 745
    metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...

  3. XM_009303598.4 → XP_009301873.1  AMP deaminase 3 isoform X4

    See identical proteins and their annotated locations for XP_009301873.1

    UniProtKB/TrEMBL
    A0A8M3AUP1
    Conserved Domains (2) summary
    PLN03055
    Location:178 → 745
    PLN03055; AMP deaminase; Provisional
    cl00281
    Location:137 → 745
    metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...

  4. XM_005169046.5 → XP_005169103.1  AMP deaminase 3 isoform X3

    UniProtKB/TrEMBL
    A0A2R8QFX5, A0A8M2BGZ9
    Related
    ENSDARP00000151889.1, ENSDART00000189424.1
    Conserved Domains (2) summary
    PLN03055
    Location:186 → 753
    PLN03055; AMP deaminase; Provisional
    cl00281
    Location:145 → 753
    metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...

  5. XM_068222773.1 → XP_068078874.1  AMP deaminase 3 isoform X2

Nucleotide Protein
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