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abcc10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 [ Danio rerio (zebrafish) ]

Gene ID: 556709, updated on 14-Nov-2024

Summary

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Official Symbol
abcc10provided by ZNC
Official Full Name
ATP-binding cassette, sub-family C (CFTR/MRP), member 10provided by ZNC
Primary source
ZFIN:ZDB-GENE-050517-24
See related
Ensembl:ENSDARG00000077988 AllianceGenome:ZFIN:ZDB-GENE-050517-24
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-69b7.2
Summary
Predicted to enable ABC-type transporter activity; ATP binding activity; and ATP hydrolysis activity. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Orthologous to human ABCC10 (ATP binding cassette subfamily C member 10). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See abcc10 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (11911399..11964702, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (11927854..11978136, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490405 Neighboring gene WAS/WASL interacting protein family, member 2a Neighboring gene serine/threonine-protein kinase pim-2-like Neighboring gene si:ch211-69b7.6 Neighboring gene zgc:64002 Neighboring gene sp2 transcription factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A New Zebrafish Model for Pseudoxanthoma Elasticum. Czimer D, et al. Front Cell Dev Biol, 2021. PMID 33768091, Free PMC Article
  2. Evolution of the vertebrate ABC gene family: analysis of gene birth and death. Annilo T, et al. Genomics, 2006 Jul. PMID 16631343
  3. Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. Dean M, et al. Annu Rev Genomics Hum Genet, 2005. PMID 16124856
  4. Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in sea lamprey and Japanese lamprey. Ren J, et al. BMC Genomics, 2015 Jun 6. PMID 26047617, Free PMC Article
  5. Expression and regulation of drug transporters in vertebrate neutrophils. Foulkes MJ, et al. Sci Rep, 2017 Jul 10. PMID 28694436, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATP-binding cassette sub-family C member 10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    11911399..11964702 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068224297.1 → XP_068080398.1  ATP-binding cassette sub-family C member 10

  2. XM_021479750.2 → XP_021335425.1  ATP-binding cassette sub-family C member 10

    UniProtKB/TrEMBL
    A0A8M9PSA7, E7F961
    Related
    ENSDARP00000101288.2, ENSDART00000115249.4
    Conserved Domains (1) summary
    cl26602
    Location:248 → 1531
    SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394803.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    20022..73325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068218641.1 → XP_068074742.1  ATP-binding cassette sub-family C member 10

  2. XM_005155760.5 → XP_005155817.1  ATP-binding cassette sub-family C member 10

    UniProtKB/TrEMBL
    A0A8M9PSA7, E7F961
    Conserved Domains (1) summary
    cl26602
    Location:248 → 1531
    SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395295.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    20022..73325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068219295.1 → XP_068075396.1  ATP-binding cassette sub-family C member 10

  2. XM_021474228.2 → XP_021329903.1  ATP-binding cassette sub-family C member 10

    UniProtKB/TrEMBL
    A0A8M9PSA7, E7F961
    Conserved Domains (1) summary
    cl26602
    Location:248 → 1531
    SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]
Nucleotide Protein Strain
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