U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ppp1r13bb protein phosphatase 1, regulatory subunit 13Bb [ Danio rerio (zebrafish) ]

Gene ID: 557278, updated on 14-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
ppp1r13bbprovided by ZNC
Official Full Name
protein phosphatase 1, regulatory subunit 13Bbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4327
See related
Ensembl:ENSDARG00000009142 AllianceGenome:ZFIN:ZDB-GENE-030131-4327
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc90h02; ppp1r13b; wu:fc90h02; si:ch211-253p18.1
Summary
Predicted to enable p53 binding activity. Predicted to act upstream of or within apoptotic process; negative regulation of cell cycle; and regulation of apoptotic process. Predicted to be active in nucleus. Orthologous to human PPP1R13B (protein phosphatase 1 regulatory subunit 13B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ppp1r13bb in Genome Data Viewer
Location:
chromosome: 20
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (20730780..20813752)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (20831096..20914079)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene reticulon 1b Neighboring gene ATP synthase membrane subunit j Neighboring gene RD3 like Neighboring gene creatine kinase, brain b Neighboring gene BRF1 general transcription factor IIIB subunit b Neighboring gene X-ray repair complementing defective repair in Chinese hamster cells 3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of differentially expressed genes between cloned and zygote-developing zebrafish (Danio rerio) embryos at the dome stage using suppression subtractive hybridization. Luo D, et al. Biol Reprod, 2009 Apr. PMID 19092113
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables p53 binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein phosphatase 1, regulatory subunit 13Bb
Names
apoptosis-stimulating protein of p53
protein phosphatase 1, regulatory (inhibitor) subunit 13B
protein phosphatase 1, regulatory (inhibitor) subunit 13Bb

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044824.2 → NP_001038289.2  protein phosphatase 1, regulatory subunit 13Bb

    See identical proteins and their annotated locations for NP_001038289.2

    Status: PROVISIONAL

    Source sequence(s)
    BC139881
    UniProtKB/TrEMBL
    A5D6T8
    Related
    ENSDARP00000047661.5, ENSDART00000047662.8
    Conserved Domains (6) summary
    TIGR02473
    Location:152 → 305
    flagell_FliJ; flagellar export protein FliJ
    cd11954
    Location:1001 → 1057
    SH3_ASPP1; Src Homology 3 domain of Apoptosis Stimulating of p53 protein 1
    cd00204
    Location:865 → 988
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam02050
    Location:225 → 327
    FliJ; Flagellar FliJ protein
    pfam12796
    Location:871 → 962
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:871 → 897
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    20730780..20813752
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009294642.4 → XP_009292917.1  protein phosphatase 1, regulatory subunit 13Bb isoform X3

    UniProtKB/TrEMBL
    A0A0R4IUG8, A0A8M3B416
    Related
    ENSDARP00000138021.1, ENSDART00000165224.2
    Conserved Domains (6) summary
    TIGR02473
    Location:152 → 305
    flagell_FliJ; flagellar export protein FliJ
    cd11954
    Location:1051 → 1107
    SH3_ASPP1; Src Homology 3 domain of Apoptosis Stimulating of p53 protein 1
    cd00204
    Location:915 → 1038
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam02050
    Location:225 → 327
    FliJ; Flagellar FliJ protein
    pfam12796
    Location:921 → 1012
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:921 → 947
    ANK; ANK repeat [structural motif]

  2. XM_068215465.1 → XP_068071566.1  protein phosphatase 1, regulatory subunit 13Bb isoform X6

  3. XM_009294640.4 → XP_009292915.1  protein phosphatase 1, regulatory subunit 13Bb isoform X1

    UniProtKB/TrEMBL
    A0A8M3AT48
    Conserved Domains (6) summary
    TIGR02473
    Location:196 → 349
    flagell_FliJ; flagellar export protein FliJ
    cd11954
    Location:1095 → 1151
    SH3_ASPP1; Src Homology 3 domain of Apoptosis Stimulating of p53 protein 1
    cd00204
    Location:959 → 1082
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:965 → 1056
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:965 → 991
    ANK; ANK repeat [structural motif]
    cl09111
    Location:250 → 369
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

  4. XM_005160501.5 → XP_005160558.1  protein phosphatase 1, regulatory subunit 13Bb isoform X4

    UniProtKB/TrEMBL
    A0A2R8QDZ7, A0A8M2B7B9
    Related
    ENSDARP00000151938.1, ENSDART00000181524.1
    Conserved Domains (6) summary
    TIGR02473
    Location:196 → 349
    flagell_FliJ; flagellar export protein FliJ
    cd11954
    Location:1045 → 1101
    SH3_ASPP1; Src Homology 3 domain of Apoptosis Stimulating of p53 protein 1
    cd00204
    Location:909 → 1032
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:915 → 1006
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:915 → 941
    ANK; ANK repeat [structural motif]
    cl09111
    Location:250 → 369
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

  5. XM_009294641.4 → XP_009292916.1  protein phosphatase 1, regulatory subunit 13Bb isoform X2

    UniProtKB/TrEMBL
    A0A8M3AKR4
    Conserved Domains (6) summary
    TIGR02473
    Location:196 → 349
    flagell_FliJ; flagellar export protein FliJ
    cd11954
    Location:1087 → 1143
    SH3_ASPP1; Src Homology 3 domain of Apoptosis Stimulating of p53 protein 1
    cd00204
    Location:951 → 1074
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:957 → 1048
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:957 → 983
    ANK; ANK repeat [structural motif]
    cl09111
    Location:250 → 377
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

  6. XM_068215464.1 → XP_068071565.1  protein phosphatase 1, regulatory subunit 13Bb isoform X5

  7. XM_009294643.4 → XP_009292918.1  protein phosphatase 1, regulatory subunit 13Bb isoform X7

    UniProtKB/TrEMBL
    A0A8M3ALG4
    Conserved Domains (7) summary
    TIGR02473
    Location:84 → 237
    flagell_FliJ; flagellar export protein FliJ
    cd11954
    Location:983 → 1039
    SH3_ASPP1; Src Homology 3 domain of Apoptosis Stimulating of p53 protein 1
    cd00204
    Location:847 → 970
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam02050
    Location:157 → 259
    FliJ; Flagellar FliJ protein
    pfam12796
    Location:853 → 944
    Ank_2; Ankyrin repeats (3 copies)
    pfam15456
    Location:105 → 177
    Uds1; Up-regulated During Septation
    sd00045
    Location:853 → 879
    ANK; ANK repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools