nom1 nucleolar protein with MIF4G domain 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nom1provided by ZNC
Official Full Name: nucleolar protein with MIF4G domain 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-060503-321
See related: Ensembl:ENSDARG00000060027 AllianceGenome:ZFIN:ZDB-GENE-060503-321
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-266o5.1
Summary: Predicted to enable RNA binding activity. Acts upstream of or within ribosome biogenesis. Predicted to be active in nucleolus. Is expressed in brain; intestine; liver; and pancreas. Orthologous to human NOM1 (nucleolar protein with MIF4G domain 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (40644872..40657791, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (40373855..40386774, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

a new mechanism involving Nom1 in controlling vertebrate exocrine pancreas formation
Title: Nom1 mediates pancreas development by regulating ribosome biogenesis in zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ribosomal small subunit biogenesis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ribosome biogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: nucleolar MIF4G domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001044832.3 → NP_001038297.3 nucleolar MIF4G domain-containing protein 1 isoform 2

Status: PROVISIONAL

Source sequence(s)

BX247878

UniProtKB/TrEMBL

A0A8M1N9E8, Q1LY16

Related

ENSDARP00000078588.4, ENSDART00000084153.6
NM_001328060.1 → NP_001314989.1 nucleolar MIF4G domain-containing protein 1 isoform 1

Status: PROVISIONAL

Source sequence(s)

BX247878

UniProtKB/TrEMBL

A0A8M1P9G3, Q1LY17

Related

ENSDARP00000122404.2, ENSDART00000142315.4

Conserved Domains (3) summary

smart00543
Location:335 → 532

MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)

cl02653
Location:629 → 735

MA3; MA3 domain

cl08298
Location:99 → 246

NAP; Nucleosome assembly protein (NAP)