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si:ch211-195b15.8 si:ch211-195b15.8 [ Danio rerio (zebrafish) ]

Gene ID: 558079, updated on 18-Sep-2024

Summary

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Official Symbol
si:ch211-195b15.8provided by ZNC
Official Full Name
si:ch211-195b15.8provided by ZNC
Primary source
ZFIN:ZDB-GENE-131127-627
See related
Ensembl:ENSDARG00000094836 AllianceGenome:ZFIN:ZDB-GENE-131127-627
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable MAP kinase tyrosine/serine/threonine phosphatase activity and protein tyrosine/threonine phosphatase activity. Predicted to be involved in negative regulation of MAPK cascade. Predicted to act upstream of or within protein dephosphorylation. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See si:ch211-195b15.8 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (32403818..32407192)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (32272029..32275483)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene protein arginine methyltransferase 1 Neighboring gene adaptor related protein complex 2 subunit alpha 1 Neighboring gene RAS related Neighboring gene proline rich Gla (G-carboxyglutamic acid) 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables MAP kinase tyrosine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables MAP kinase tyrosine/serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
dual specificity protein phosphatase 16
Names
dual specificity protein phosphatase 16-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    32403818..32407192
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_681250.8 → XP_686342.1  dual specificity protein phosphatase 16

    UniProtKB/TrEMBL
    A0A8N7UVQ0, X1WCB8
    Related
    ENSDARP00000127861.1, ENSDART00000156982.2
    Conserved Domains (1) summary
    cd00127
    Location:13 → 149
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
Nucleotide Protein Strain
Heading Accession and Version

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