peli1b pellino E3 ubiquitin protein ligase 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: peli1bprovided by ZNC
Official Full Name: pellino E3 ubiquitin protein ligase 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-061027-372
See related: Ensembl:ENSDARG00000044083 AllianceGenome:ZFIN:ZDB-GENE-061027-372
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: peli1; wu:fd12d01; zgc:153297
Summary: Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within brain development. Is expressed in several structures, including brain; hindbrain neural rod; mesoderm; shield; and tail bud. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human PELI1 (pellino E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (24479880..24521382, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (24461479..24502981, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within brain development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein K48-linked ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein polyubiquitination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of Toll signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase pellino homolog 1b

Names: pellino homolog 1; pellino homolog 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.