coq7 coenzyme Q7 homolog, ubiquinone (yeast) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: coq7provided by ZNC
Official Full Name: coenzyme Q7 homolog, ubiquinone (yeast)provided by ZNC
Primary source: ZFIN:ZDB-GENE-070209-262
See related: Ensembl:ENSDARG00000062594 AllianceGenome:ZFIN:ZDB-GENE-070209-262
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cat5; clk-1; im:7159541; zgc:158731
Summary: Predicted to enable 3-demethoxyubiquinol 3-hydroxylase activity. Predicted to be involved in several processes, including determination of adult lifespan; regulation of reactive oxygen species metabolic process; and ubiquinone biosynthetic process. Predicted to be located in membrane and mitochondrion. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be active in mitochondrial inner membrane and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy 9 and primary coenzyme Q10 deficiency 8. Orthologous to human COQ7 (coenzyme Q7, hydroxylase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (10982786..10988741, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (10747359..10753314, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 3-demethoxyubiquinol 3-hydroxylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 3-demethoxyubiquinol 3-hydroxylase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in determination of adult lifespan	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of gene expression	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of reactive oxygen species metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in ubiquinone biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ubiquinone biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in ubiquinone biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extrinsic component of mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 5-demethoxyubiquinone hydroxylase, mitochondrial

NP_001076480.1

EC 1.14.99.60

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.