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hnrnpd heterogeneous nuclear ribonucleoprotein D [ Danio rerio (zebrafish) ]

Gene ID: 560522, updated on 2-Nov-2024

Summary

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Official Symbol
hnrnpdprovided by ZNC
Official Full Name
heterogeneous nuclear ribonucleoprotein Dprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070424-97
See related
Ensembl:ENSDARG00000059246 AllianceGenome:ZFIN:ZDB-GENE-070424-97
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fa28b06; zgc:162951
Summary
Enables mRNA 3'-UTR binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in chromatin. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Orthologous to human HNRNPD (heterogeneous nuclear ribonucleoprotein D). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See hnrnpd in Genome Data Viewer
Location:
chromosome: 10
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (5000623..5017022, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (5000319..5016737, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene methionine adenosyltransferase II, alpha-like Neighboring gene si:ch73-234b20.5 Neighboring gene heterogeneous nuclear ribonucleoprotein D-like Neighboring gene enolase-phosphatase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1. Poganik JR, et al. FASEB J, 2019 Dec. PMID 31665914, Free PMC Article
  2. Genome wide analysis of 3' UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish. Vejnar CE, et al. Genome Res, 2019 Jul. PMID 31227602, Free PMC Article
  3. An evolutionary approach to recover genes predominantly expressed in the testes of the zebrafish, chicken and mouse. Fouchécourt S, et al. BMC Evol Biol, 2019 Jul 3. PMID 31269894, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of macromolecule biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of RNA metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
heterogeneous nuclear ribonucleoprotein D0

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110460.1 → NP_001103930.1  heterogeneous nuclear ribonucleoprotein D0

    See identical proteins and their annotated locations for NP_001103930.1

    Status: PROVISIONAL

    Source sequence(s)
    BC139674
    UniProtKB/TrEMBL
    A4QP67
    Related
    ENSDARP00000092188.3, ENSDART00000101414.4
    Conserved Domains (3) summary
    cd12575
    Location:56 → 129
    RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
    cd12583
    Location:140 → 214
    RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
    pfam08143
    Location:3 → 54
    CBFNT; CBFNT (NUC161) domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    5000623..5017022 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005155547.4 → XP_005155604.1  heterogeneous nuclear ribonucleoprotein D0 isoform X2

    See identical proteins and their annotated locations for XP_005155604.1

    UniProtKB/TrEMBL
    A0A2R8QHK1, A0A8M9QC46
    Conserved Domains (3) summary
    cd12575
    Location:56 → 129
    RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
    cd12583
    Location:140 → 214
    RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
    pfam08143
    Location:3 → 54
    CBFNT; CBFNT (NUC161) domain

  2. XM_005155545.4 → XP_005155602.1  heterogeneous nuclear ribonucleoprotein D0 isoform X1

    See identical proteins and their annotated locations for XP_005155602.1

    UniProtKB/TrEMBL
    A0A8M2B1M3, F1Q8A5
    Conserved Domains (3) summary
    cd12575
    Location:56 → 129
    RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
    cd12583
    Location:140 → 214
    RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
    pfam08143
    Location:3 → 54
    CBFNT; CBFNT (NUC161) domain

  3. XM_021479184.2 → XP_021334859.1  heterogeneous nuclear ribonucleoprotein D0 isoform X2

    UniProtKB/TrEMBL
    A0A2R8QHK1, A0A8M9QC46
    Conserved Domains (3) summary
    cd12575
    Location:56 → 129
    RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
    cd12583
    Location:140 → 214
    RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
    pfam08143
    Location:3 → 54
    CBFNT; CBFNT (NUC161) domain

  4. XM_005155546.4 → XP_005155603.1  heterogeneous nuclear ribonucleoprotein D0 isoform X2

    See identical proteins and their annotated locations for XP_005155603.1

    UniProtKB/TrEMBL
    A0A2R8QHK1, A0A8M9QC46
    Related
    ENSDARP00000153486.1, ENSDART00000191857.1
    Conserved Domains (3) summary
    cd12575
    Location:56 → 129
    RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
    cd12583
    Location:140 → 214
    RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
    pfam08143
    Location:3 → 54
    CBFNT; CBFNT (NUC161) domain

  5. XM_005155544.4 → XP_005155601.1  heterogeneous nuclear ribonucleoprotein D0 isoform X1

    See identical proteins and their annotated locations for XP_005155601.1

    UniProtKB/TrEMBL
    A0A8M2B1M3, F1Q8A5
    Conserved Domains (3) summary
    cd12575
    Location:56 → 129
    RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
    cd12583
    Location:140 → 214
    RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
    pfam08143
    Location:3 → 54
    CBFNT; CBFNT (NUC161) domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394763.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    54967..71417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395286.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    48463..64909 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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