tifa TRAF interacting protein with forkhead associated domain [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tifaprovided by ZNC
Official Full Name: TRAF interacting protein with forkhead associated domainprovided by ZNC
Primary source: ZFIN:ZDB-GENE-160728-113
See related: Ensembl:ENSDARG00000091111 AllianceGenome:ZFIN:ZDB-GENE-160728-113
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-15b10.6
Summary: Predicted to act upstream of or within innate immune response and positive regulation of canonical NF-kappaB signal transduction. Orthologous to human TIFA (TRAF interacting protein with forkhead associated domain). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (22788718..22790411, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (22517566..22519284, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within immune system process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within innate immune response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: TRAF-interacting protein with FHA domain-containing protein A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001386546.1 → NP_001373475.1 TRAF-interacting protein with FHA domain-containing protein A

Status: VALIDATED

Source sequence(s)

AL928799

UniProtKB/TrEMBL

A0A1D5NSL5, A0A8M2BJQ1

Related

ENSDARP00000142832.1, ENSDART00000173496.2

Conserved Domains (1) summary

cd00060
Location:38 → 127

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...