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lin54 lin-54 DREAM MuvB core complex component [ Danio rerio (zebrafish) ]

Gene ID: 560688, updated on 9-Dec-2024

Summary

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Official Symbol
lin54provided by ZNC
Official Full Name
lin-54 DREAM MuvB core complex componentprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-440
See related
Ensembl:ENSDARG00000063194 AllianceGenome:ZFIN:ZDB-GENE-060929-440
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:152921
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human LIN54 (lin-54 DREAM MuvB core complex component). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See lin54 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (11327137..11353101, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (11369117..11394863, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene KIAA1958 ortholog Neighboring gene ints3 and nabp interacting protein Neighboring gene COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) Neighboring gene placenta associated 8, tandem duplicate 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. lin9 is required for mitosis and cell survival during early zebrafish development. Kleinschmidt MA, et al. J Biol Chem, 2009 May 8. PMID 19278998, Free PMC Article
  2. Loss of smarcad1a accelerates tumorigenesis of malignant peripheral nerve sheath tumors in zebrafish. Han H, et al. Genes Chromosomes Cancer, 2021 Nov. PMID 34296799, Free PMC Article
  3. An evolutionary approach to recover genes predominantly expressed in the testes of the zebrafish, chicken and mouse. Fouchécourt S, et al. BMC Evol Biol, 2019 Jul 3. PMID 31269894, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC152921

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein lin-54 homolog
Names
lin-54 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076567.1 → NP_001070035.1  protein lin-54 homolog

    See identical proteins and their annotated locations for NP_001070035.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124175
    UniProtKB/Swiss-Prot
    Q08CM4
    Related
    ENSDARP00000086543.5, ENSDART00000092110.6
    Conserved Domains (1) summary
    pfam03638
    Location:619 → 654
    TCR; Tesmin/TSO1-like CXC domain, cysteine-rich domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    11327137..11353101 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009305164.4 → XP_009303439.1  protein lin-54 homolog isoform X1

    See identical proteins and their annotated locations for XP_009303439.1

    UniProtKB/TrEMBL
    A0A8M3B625, F1QDM3
    Conserved Domains (1) summary
    pfam03638
    Location:619 → 654
    TCR; Tesmin/TSO1-like CXC domain, cysteine-rich domain

  2. XM_005155601.5 → XP_005155658.1  protein lin-54 homolog isoform X1

    See identical proteins and their annotated locations for XP_005155658.1

    UniProtKB/TrEMBL
    A0A8M3B625, F1QDM3
    Conserved Domains (1) summary
    pfam03638
    Location:619 → 654
    TCR; Tesmin/TSO1-like CXC domain, cysteine-rich domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08CM4.1 GenPept UniProtKB/Swiss-Prot:Q08CM4

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