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eif3eb eukaryotic translation initiation factor 3, subunit E, b [ Danio rerio (zebrafish) ]

Gene ID: 561049, updated on 2-Nov-2024

Summary

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Official Symbol
eif3ebprovided by ZNC
Official Full Name
eukaryotic translation initiation factor 3, subunit E, bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050208-283
See related
Ensembl:ENSDARG00000002549 AllianceGenome:ZFIN:ZDB-GENE-050208-283
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
eif3s6b; im:7147439
Summary
Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Predicted to be active in nucleus. Orthologous to human EIF3E (eukaryotic translation initiation factor 3 subunit E). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See eif3eb in Genome Data Viewer
Location:
chromosome: 19
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (22624269..22664128, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (23039946..23079831, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene F-box and leucine-rich repeat protein 6 Neighboring gene epiplakin 1 Neighboring gene plectin a Neighboring gene uncharacterized LOC137488510 Neighboring gene uncharacterized LOC137488511 Neighboring gene transmembrane protein 74

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Characterization of Biological Pathways Regulating Acute Cold Resistance of Zebrafish. Ren J, et al. Int J Mol Sci, 2021 Mar 16. PMID 33809683, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to translation initiation factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in formation of cytoplasmic translation initiation complex IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within translational initiation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational initiation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic 43S preinitiation complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic 48S preinitiation complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation initiation factor 3 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic translation initiation factor 3 complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation initiation factor 3 complex ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of eukaryotic translation initiation factor 3 complex, eIF3e IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
eukaryotic translation initiation factor 3 subunit E-B
Names
eukaryotic translation initiation factor 3, subunit 6b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362621.1 → NP_001349550.1  eukaryotic translation initiation factor 3 subunit E-B

    Status: VALIDATED

    Source sequence(s)
    BX957242
    UniProtKB/Swiss-Prot
    Q1LUA7, Q1LUA8
    UniProtKB/TrEMBL
    A0A8M2BHD7, F1QHS3
    Related
    ENSDARP00000003276.8, ENSDART00000023926.11
    Conserved Domains (2) summary
    pfam01399
    Location:291 → 395
    PCI; PCI domain
    pfam09440
    Location:5 → 138
    eIF3_N; eIF3 subunit 6 N terminal domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    22624269..22664128 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001044951.1: Suppressed sequence

    Description
    NM_001044951.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1LUA8.2 GenPept UniProtKB/Swiss-Prot:Q1LUA8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.