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si:ch73-206d17.1 si:ch73-206d17.1 [ Danio rerio (zebrafish) ]

Gene ID: 561155, updated on 14-Nov-2024

Summary

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Official Symbol
si:ch73-206d17.1provided by ZNC
Official Full Name
si:ch73-206d17.1provided by ZNC
Primary source
ZFIN:ZDB-GENE-090313-143
See related
Ensembl:ENSDARG00000086159 AllianceGenome:ZFIN:ZDB-GENE-090313-143
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
lyn
Summary
Predicted to enable protein tyrosine kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human STYK1 (serine/threonine/tyrosine kinase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See si:ch73-206d17.1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (26491943..26498442)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (26565397..26571643)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene lysine-specific demethylase 9 Neighboring gene membrane associated guanylate kinase, WW and PDZ domain containing 3a Neighboring gene si:dkey-205h13.2 Neighboring gene transmembrane protein 269

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Conservation and early expression of zebrafish tyrosine kinases support the utility of zebrafish as a model for tyrosine kinase biology. Challa AK, et al. Zebrafish, 2013 Sep. PMID 23234507, Free PMC Article
  2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables non-membrane spanning protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tyrosine-protein kinase STYK1
Names
styk1b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    26491943..26498442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_684560.7 → XP_689652.2  tyrosine-protein kinase STYK1 isoform X1

    UniProtKB/TrEMBL
    A0A8N7UVU0, E7FGQ0
    Related
    ENSDARP00000115394.1, ENSDART00000132905.2
    Conserved Domains (2) summary
    pfam07714
    Location:102 → 362
    Pkinase_Tyr; Protein tyrosine kinase
    cl21453
    Location:102 → 363
    PKc_like; Protein Kinases, catalytic domain

  2. XM_068216911.1 → XP_068073012.1  tyrosine-protein kinase STYK1 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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