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crebzf CREB/ATF bZIP transcription factor [ Danio rerio (zebrafish) ]

Gene ID: 562093, updated on 2-Nov-2024

Summary

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Official Symbol
crebzfprovided by ZNC
Official Full Name
CREB/ATF bZIP transcription factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8015
See related
Ensembl:ENSDARG00000089787 AllianceGenome:ZFIN:ZDB-GENE-030131-8015
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj46h08; wu:fj46h08
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human CREBZF (CREB/ATF bZIP transcription factor). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See crebzf in Genome Data Viewer
Location:
chromosome: 10
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (29265471..29267306)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (29378838..29382334)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 83 Neighboring gene synaptotagmin-like 2a Neighboring gene transmembrane protein 126A Neighboring gene discs, large homolog 2 (Drosophila) Neighboring gene uncharacterized LOC137496592

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Tryptophan Hydroxylase 2 Deficiency Modifies the Effects of Fluoxetine and Pargyline on the Behavior, 5-HT- and BDNF-Systems in the Brain of Zebrafish (Danio rerio). Evsiukova VS, et al. Int J Mol Sci, 2021 Nov 27. PMID 34884655, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CREB/ATF bZIP transcription factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    29265471..29267306
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009305487.4 → XP_009303762.1  CREB/ATF bZIP transcription factor isoform X2

    UniProtKB/TrEMBL
    A0A8M3B6E6
    Conserved Domains (1) summary
    cd14706
    Location:107 → 160
    bZIP_CREBZF; Basic leucine zipper (bZIP) domain of CREBZF/Zhangfei transcription factor and similar proteins: a DNA-binding and dimerization domain

  2. XM_009305485.4 → XP_009303760.1  CREB/ATF bZIP transcription factor isoform X1

    See identical proteins and their annotated locations for XP_009303760.1

    UniProtKB/TrEMBL
    A0A8M3AWY9, X1WCW7
    Related
    ENSDARP00000128064.1, ENSDART00000155390.3
    Conserved Domains (1) summary
    cd14706
    Location:107 → 160
    bZIP_CREBZF; Basic leucine zipper (bZIP) domain of CREBZF/Zhangfei transcription factor and similar proteins: a DNA-binding and dimerization domain
Nucleotide Protein Strain
Heading Accession and Version

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