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dlgap4a discs, large (Drosophila) homolog-associated protein 4a [ Danio rerio (zebrafish) ]

Gene ID: 562742, updated on 14-Nov-2024

Summary

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Official Symbol
dlgap4aprovided by ZNC
Official Full Name
discs, large (Drosophila) homolog-associated protein 4aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080219-51
See related
AllianceGenome:ZFIN:ZDB-GENE-080219-51
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
dlgap4; zgc:171808
Summary
Predicted to enable molecular adaptor activity. Predicted to be involved in modulation of chemical synaptic transmission. Predicted to act upstream of or within signaling. Predicted to be active in glutamatergic synapse and postsynaptic specialization. Orthologous to human DLGAP4 (DLG associated protein 4). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
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Genomic context

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See dlgap4a in Genome Data Viewer
Location:
chromosome: 23
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (42836125..43125969, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (42943521..43233354, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a Neighboring gene myosin, light chain 9a, regulatory Neighboring gene si:dkey-65j6.2 Neighboring gene transglutaminase 2, C polypeptide A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. Sundström G, et al. PLoS One, 2010 May 6. PMID 20463905, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC171808

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within signaling IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
discs, large (Drosophila) homolog-associated protein 4a; disks large-associated protein 4
Names
discs, large homolog-associated protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    42836125..43125969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021470049.2 → XP_021325724.1  disks large-associated protein 4

    UniProtKB/TrEMBL
    A0A8M9PLE1
    Conserved Domains (1) summary
    pfam03359
    Location:713 → 1034
    GKAP; Guanylate-kinase-associated protein (GKAP) protein
Nucleotide Protein Strain
Heading Accession and Version

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