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si:dkey-26g8.5 si:dkey-26g8.5 [ Danio rerio (zebrafish) ]

Gene ID: 563390, updated on 14-Nov-2024

Summary

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Official Symbol
si:dkey-26g8.5provided by ZNC
Official Full Name
si:dkey-26g8.5provided by ZNC
Primary source
ZFIN:ZDB-GENE-121214-19
See related
Ensembl:ENSDARG00000089750 AllianceGenome:ZFIN:ZDB-GENE-121214-19
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ctsl
Summary
Predicted to enable cysteine-type peptidase activity. Predicted to act upstream of or within proteolysis. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See si:dkey-26g8.5 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (16919348..16923163, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (16797537..16801288, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108191771 Neighboring gene uncharacterized LOC101886821 Neighboring gene zgc:174855 Neighboring gene zgc:174153

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolutionary History of Cathepsin L (L-like) Family Genes in Vertebrates. Zhou J, et al. Int J Biol Sci, 2015. PMID 26221069, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC174857

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC563390
Names
cathepsin L1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001103115.2 → NP_001096585.1  uncharacterized protein LOC563390 precursor

    See identical proteins and their annotated locations for NP_001096585.1

    Status: VALIDATED

    Source sequence(s)
    BX000534
    UniProtKB/TrEMBL
    A0A8M1NEK9, A7MCR8, A8E587
    Related
    ENSDARP00000096850.3, ENSDART00000106072.5
    Conserved Domains (2) summary
    smart00848
    Location:28 → 86
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    pfam00112
    Location:115 → 334
    Peptidase_C1; Papain family cysteine protease

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    16919348..16923163 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068224609.1 → XP_068080710.1  uncharacterized protein LOC563390 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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