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znf76 zinc finger protein 76 [ Danio rerio (zebrafish) ]

Gene ID: 564210, updated on 14-Nov-2024

Summary

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Official Symbol
znf76provided by ZNC
Official Full Name
zinc finger protein 76provided by ZNC
Primary source
ZFIN:ZDB-GENE-061027-379
See related
Ensembl:ENSDARG00000013279 AllianceGenome:ZFIN:ZDB-GENE-061027-379
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153635
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is expressed in brain; eye; gut; and trigeminal placode. Orthologous to human ZNF76 (zinc finger protein 76). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See znf76 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (737211..753395)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (699498..715672)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like 8A Neighboring gene zgc:162255 Neighboring gene retinoblastoma binding protein 5 Neighboring gene cryptochrome circadian regulator 3b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Znf76 is associated with development of the eyes, midbrain, MHB, and hindbrain in zebrafish embryos. Jung J, et al. Anim Cells Syst (Seoul), 2019 Feb. PMID 30834156, Free PMC Article
  2. march5 Governs the Convergence and Extension Movement for Organization of the Telencephalon and Diencephalon in Zebrafish Embryos. Jung J, et al. Mol Cells, 2020 Jan 31. PMID 31910335, Free PMC Article
  3. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC153635

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 76

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077610.1 → NP_001071078.1  zinc finger protein 76

    See identical proteins and their annotated locations for NP_001071078.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124408
    UniProtKB/TrEMBL
    B2GS63, Q05AL8
    Related
    ENSDARP00000020208.7, ENSDART00000017305.8
    Conserved Domains (3) summary
    sd00017
    Location:170 → 192
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:244 → 271
    zf-H2C2_2; Zinc-finger double domain
    pfam17017
    Location:228 → 349
    zf-C2H2_aberr; Aberrant zinc-finger

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    737211..753395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068216332.1 → XP_068072433.1  zinc finger protein 76 isoform X2

  2. XM_009295759.3 → XP_009294034.1  zinc finger protein 76 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AUB7
    Conserved Domains (3) summary
    sd00017
    Location:188 → 210
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:262 → 289
    zf-H2C2_2; Zinc-finger double domain
    pfam17017
    Location:246 → 367
    zf-C2H2_aberr; Aberrant zinc-finger

  3. XM_009295760.4 → XP_009294035.1  zinc finger protein 76 isoform X2

    See identical proteins and their annotated locations for XP_009294035.1

    UniProtKB/TrEMBL
    B2GS63, Q05AL8
    Conserved Domains (3) summary
    sd00017
    Location:170 → 192
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:244 → 271
    zf-H2C2_2; Zinc-finger double domain
    pfam17017
    Location:228 → 349
    zf-C2H2_aberr; Aberrant zinc-finger
Nucleotide Protein Strain
Heading Accession and Version

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