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fastkd2 FAST kinase domains 2 [ Danio rerio (zebrafish) ]

Gene ID: 564382, updated on 2-Nov-2024

Summary

Official Symbol
fastkd2provided by ZNC
Official Full Name
FAST kinase domains 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-090313-7
See related
Ensembl:ENSDARG00000074031 AllianceGenome:ZFIN:ZDB-GENE-090313-7
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-103i6.5
Summary
Predicted to enable RNA binding activity. Predicted to be involved in mitochondrial RNA processing and regulation of mitochondrial mRNA stability. Predicted to act upstream of or within phosphorylation. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Used to study combined oxidative phosphorylation deficiency. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 44. Orthologous to human FASTKD2 (FAST kinase domains 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See fastkd2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (6221936..6243819)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (5527714..5545996)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene protein kinase, AMP-activated, gamma 3a non-catalytic subunit Neighboring gene reticulophagy regulator family member 2 Neighboring gene malate dehydrogenase 1B, NAD (soluble) Neighboring gene general transcription factor IIIC, polypeptide 3 Neighboring gene uncharacterized LOC137495397

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in mitochondrial RNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of mitochondrial mRNA stability IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of mitochondrial mRNA stability IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
is_active_in ribonucleoprotein granule IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
FAST kinase domain-containing protein 2; FAST kinase domain-containing protein 2, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    6221936..6243819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021475935.2XP_021331610.1  FAST kinase domain-containing protein 2, mitochondrial

    UniProtKB/TrEMBL
    A0A8N7UR43
    Conserved Domains (2) summary
    smart00952
    Location:577628
    RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
    pfam06743
    Location:394463
    FAST_1; FAST kinase-like protein, subdomain 1
  2. XM_687718.10XP_692810.5  FAST kinase domain-containing protein 2, mitochondrial

    UniProtKB/TrEMBL
    A0A8N7UR43
    Related
    ENSDARP00000122274.1, ENSDART00000145378.3
    Conserved Domains (2) summary
    smart00952
    Location:577628
    RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
    pfam06743
    Location:394463
    FAST_1; FAST kinase-like protein, subdomain 1