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cpne2 copine II [ Danio rerio (zebrafish) ]

Gene ID: 565225, updated on 2-Nov-2024

Summary

Official Symbol
cpne2provided by ZNC
Official Full Name
copine IIprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7896
See related
Ensembl:ENSDARG00000007753 AllianceGenome:ZFIN:ZDB-GENE-030131-7896
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj39e04; wu:fj39e04; si:ch211-122c9.1
Summary
Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Predicted to be active in plasma membrane. Orthologous to human CPNE2 (copine 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See cpne2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (17660373..17703462)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (17671082..17714396)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene cholesteryl ester transfer protein, plasma Neighboring gene NLR family, CARD domain containing 5 Neighboring gene proteasome activator subunit 3 interacting protein 1 Neighboring gene ring finger and SPRY domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium-dependent phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular response to calcium ion IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045075.2NP_001038540.1  copine-2

    Status: PROVISIONAL

    Source sequence(s)
    BX470074, BX470170
    UniProtKB/TrEMBL
    A0A8N7UYA4, Q1LX40
    Related
    ENSDARP00000002576.8, ENSDART00000021213.9
    Conserved Domains (3) summary
    cd04047
    Location:171283
    C2B_Copine; C2 domain second repeat in Copine
    cd04048
    Location:40157
    C2A_Copine; C2 domain first repeat in Copine
    cd01459
    Location:294545
    vWA_copine_like; VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae. ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    17660373..17703462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159116.5XP_005159173.1  copine-2 isoform X1

    UniProtKB/TrEMBL
    A0A2R8Q0R6, A0A8M2B629
    Related
    ENSDARP00000146042.1, ENSDART00000186279.1
    Conserved Domains (3) summary
    cd04047
    Location:153265
    C2B_Copine; C2 domain second repeat in Copine
    cd04048
    Location:22139
    C2A_Copine; C2 domain first repeat in Copine
    cd01459
    Location:276527
    vWA_copine_like; VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae. ...