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dmtn dematin actin binding protein [ Danio rerio (zebrafish) ]

Gene ID: 565367, updated on 2-Nov-2024

Summary

Official Symbol
dmtnprovided by ZNC
Official Full Name
dematin actin binding proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9438
See related
Ensembl:ENSDARG00000013110 AllianceGenome:ZFIN:ZDB-GENE-030131-9438
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
epb49; fj78f01; wu:fj78f01; wu:fq17b06; wu:cegs2341; si:dkeyp-66d7.2
Summary
Predicted to enable actin filament binding activity. Predicted to be involved in lamellipodium assembly. Predicted to act upstream of or within cytoskeleton organization. Predicted to be located in cytoplasm. Predicted to be active in actin cytoskeleton and plasma membrane. Is expressed in blood; nervous system; and ventral mesoderm. Orthologous to human DMTN (dematin actin binding protein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See dmtn in Genome Data Viewer
Location:
chromosome: 10
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (20108432..20147593)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (20151051..20190212)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene exportin 7 Neighboring gene polysaccharide biosynthesis domain containing 1 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 7b Neighboring gene protein phosphatase 3, catalytic subunit, gamma isozyme, b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
involved_in lamellipodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
dematin
Names
erythrocyte membrane protein band 4.9 (dematin)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001201409.1NP_001188338.1  dematin

    See identical proteins and their annotated locations for NP_001188338.1

    Status: VALIDATED

    Source sequence(s)
    BM023921, CR450836, EH436384
    UniProtKB/TrEMBL
    A0A8M2B209, E7FCX5
    Related
    ENSDARP00000064614.7, ENSDART00000064615.7
    Conserved Domains (2) summary
    pfam02209
    Location:363397
    VHP; Villin headpiece domain
    pfam16182
    Location:9361
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    20108432..20147593
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005155315.5XP_005155372.2  dematin isoform X1

    Related
    ENSDARP00000127950.1, ENSDART00000142708.4

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394779.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    151248..190409
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395287.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    14020..53181
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)