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otomp otolith matrix protein [ Danio rerio (zebrafish) ]

Gene ID: 565818, updated on 2-Nov-2024

Summary

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Official Symbol
otompprovided by ZNC
Official Full Name
otolith matrix proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040709-1
See related
Ensembl:ENSDARG00000040306 AllianceGenome:ZFIN:ZDB-GENE-040709-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
omp; omp-1; zomp1; im:6904989; wu:fc44d11
Summary
Acts upstream of or within otolith development. Predicted to be located in extracellular region. Predicted to be active in endosome; extracellular space; and plasma membrane. Is expressed in epithalamus; otic vesicle; and vestibuloauditory system. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See otomp in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (41504752..41518340, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (41655412..41669000, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene heparan sulfate 6-O-sulfotransferase 1a Neighboring gene uncharacterized LOC137488025 Neighboring gene uncharacterized LOC110438100 Neighboring gene activin A receptor, type 1 like Neighboring gene D-2-hydroxyglutarate dehydrogenase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zona pellucida domain-containing protein β-tectorin is crucial for zebrafish proper inner ear development. Yang CH, et al. PLoS One, 2011. PMID 21829695, Free PMC Article
  2. Alteration of organ size and allometric scaling by organ-specific targeting of IGF signaling. Kamei H, et al. Gen Comp Endocrinol, 2021 Dec 1. PMID 34606746
  3. Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio. Hughes I, et al. Dev Biol, 2004 Dec 15. PMID 15581873, Free PMC Article
  4. Otolith matrix proteins OMP-1 and Otolin-1 are necessary for normal otolith growth and their correct anchoring onto the sensory maculae. Murayama E, et al. Mech Dev, 2005 Jun. PMID 15905077
  5. Otoc1: a novel otoconin-90 ortholog required for otolith mineralization in zebrafish. Petko JA, et al. Dev Neurobiol, 2008 Feb 1. PMID 18000829, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in iron ion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within otolith development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within otolith development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in recycling endosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
otolith matrix protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045087.1 → NP_001038552.1  otolith matrix protein 1 precursor

    See identical proteins and their annotated locations for NP_001038552.1

    Status: PROVISIONAL

    Source sequence(s)
    AY681353
    UniProtKB/Swiss-Prot
    Q0VIL3, Q6DGA2
    Related
    ENSDARP00000106982.3, ENSDART00000130830.3
    Conserved Domains (2) summary
    smart00094
    Location:27 → 363
    TR_FER; Transferrin
    cd13529
    Location:27 → 363
    PBP2_transferrin; Transferrin family of the type 2 periplasmic-binding protein superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    41504752..41518340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0VIL3.1 GenPept UniProtKB/Swiss-Prot:Q0VIL3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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