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etnk1 ethanolamine kinase 1 [ Danio rerio (zebrafish) ]

Gene ID: 565971, updated on 2-Nov-2024

Summary

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Official Symbol
etnk1provided by ZNC
Official Full Name
ethanolamine kinase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030328-21
See related
Ensembl:ENSDARG00000019420 AllianceGenome:ZFIN:ZDB-GENE-030328-21
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb661; wu:fb38f12; wu:fj21d12; si:dkey-13i19.1
Summary
Predicted to enable ethanolamine kinase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm. Is expressed in pronephric duct. Orthologous to human ETNK1 (ethanolamine kinase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See etnk1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (16885801..16906064)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (16896779..16916406)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene thymopoietin a Neighboring gene serine/threonine kinase receptor associated protein Neighboring gene uncharacterized LOC137491538 Neighboring gene SRY-box transcription factor 5 Neighboring gene uncharacterized LOC137491396

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Regulation of spermatogonial development by Fsh: The complementary roles of locally produced Igf and Wnt signaling molecules in adult zebrafish testis. Safian D, et al. Gen Comp Endocrinol, 2019 Dec 1. PMID 31415728
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ethanolamine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ethanolamine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphatidylethanolamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ethanolamine kinase 1
XP_009298589.1
XP_689471.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    16885801..16906064
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_684379.10 → XP_689471.3  ethanolamine kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8N7T5U8, Q5RGY0
    Related
    ENSDARP00000019763.7, ENSDART00000017726.8
    Conserved Domains (1) summary
    cd05157
    Location:46 → 348
    ETNK_euk; Euykaryotic Ethanolamine kinase

  2. XM_009300314.4 → XP_009298589.1  ethanolamine kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M3ARF6
    Conserved Domains (1) summary
    cl21453
    Location:46 → 231
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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