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ano10a anoctamin 10a [ Danio rerio (zebrafish) ]

Gene ID: 566425, updated on 4-Jan-2025

Summary

Official Symbol
ano10aprovided by ZNC
Official Full Name
anoctamin 10aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050913-43
See related
Ensembl:ENSDARG00000057736 AllianceGenome:ZFIN:ZDB-GENE-050913-43
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ano10; fc37b04; wu:fc37b04; zgc:114140
Summary
Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 10. Orthologous to human ANO10 (anoctamin 10). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See ano10a in Genome Data Viewer
Location:
chromosome: 16
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (7985886..8041348)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (8067642..8125189)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487833 Neighboring gene abhydrolase domain containing 5, lysophosphatidic acid acyltransferase a Neighboring gene SNF related kinase a Neighboring gene protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC114140

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chloride channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in chloride transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
anoctamin-10
Names
transmembrane protein 16K

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030206.1NP_001025377.1  anoctamin-10

    See identical proteins and their annotated locations for NP_001025377.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097195
    UniProtKB/Swiss-Prot
    Q4V8U5
    Related
    ENSDARP00000112117.1, ENSDART00000126041.2
    Conserved Domains (1) summary
    pfam04547
    Location:200626
    Anoctamin; Calcium-activated chloride channel

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    7985886..8041348
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)