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olig3 oligodendrocyte transcription factor 3 [ Danio rerio (zebrafish) ]

Gene ID: 566728, updated on 2-Nov-2024

Summary

Official Symbol
olig3provided by ZNC
Official Full Name
oligodendrocyte transcription factor 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-080903-1
See related
Ensembl:ENSDARG00000074253 AllianceGenome:ZFIN:ZDB-GENE-080903-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Predicted to be involved in axon development; positive regulation of transcription by RNA polymerase II; and sensory organ development. Predicted to act upstream of or within cell differentiation and nervous system development. Predicted to be active in nucleus. Is expressed in several structures, including brain; neural plate; neural tube; posterior neural keel; and presumptive diencephalon. Orthologous to human OLIG3 (oligodendrocyte transcription factor 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See olig3 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (1305351..1308020, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (1175060..1177729, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene p53 apoptosis effector related to pmp22 Neighboring gene tumor necrosis factor, alpha-induced protein 3 Neighboring gene si:ch73-52p7.1 Neighboring gene growth differentiation factor 10b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables E-box binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in axon development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in sensory organ development IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
oligodendrocyte transcription factor 3
Names
Oligo3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110393.1NP_001103863.1  oligodendrocyte transcription factor 3

    See identical proteins and their annotated locations for NP_001103863.1

    Status: PROVISIONAL

    Source sequence(s)
    BC154834
    UniProtKB/TrEMBL
    A0A8M1NGJ0, A8WGS8
    Related
    ENSDARP00000157677.1, ENSDART00000111052.4
    Conserved Domains (1) summary
    pfam00010
    Location:76129
    HLH; Helix-loop-helix DNA-binding domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    1305351..1308020 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)