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lye lymphocyte antigen-6, epidermis [ Danio rerio (zebrafish) ]

Gene ID: 567961, updated on 4-Jan-2025

Summary

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Official Symbol
lyeprovided by ZNC
Official Full Name
lymphocyte antigen-6, epidermisprovided by ZNC
Primary source
ZFIN:ZDB-GENE-120104-1
See related
AllianceGenome:ZFIN:ZDB-GENE-120104-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fb36d12
Summary
Is expressed in EVL; integument; olfactory placode; pectoral fin; and pharyngeal arch. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See lye in Genome Data Viewer
Location:
chromosome: 19
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (18749603..18751612)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (17461639..17463680)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene VPS52 subunit of GARP complex Neighboring gene ST3 beta-galactoside alpha-2,3-sialyltransferase 1, like 3 Neighboring gene uncharacterized LOC568019 Neighboring gene uncharacterized LOC137488498 Neighboring gene chloride intracellular channel 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization. Fujihara Y, et al. Proc Natl Acad Sci U S A, 2021 Sep 28. PMID 34556579, Free PMC Article
  2. The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization. Herberg S, et al. Science, 2018 Sep 7. PMID 30190407, Free PMC Article
  3. Identification and expression of a novel member of Ly-6 superfamily in zebrafish Denio rerio. Ji D, et al. Dev Genes Evol, 2012 Apr. PMID 22415300
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
lymphocyte antigen-6, epidermis

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386338.1 → NP_001373267.1  lymphocyte antigen-6, epidermis precursor

    Status: VALIDATED

    Source sequence(s)
    FP067396
    UniProtKB/TrEMBL
    A0A8N7TFX4
    Conserved Domains (1) summary
    cl10471
    Location:24 → 99
    LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    18749603..18751612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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