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cox14 cytochrome c oxidase assembly factor COX14 [ Danio rerio (zebrafish) ]

Gene ID: 568423, updated on 2-Nov-2024

Summary

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Official Symbol
cox14provided by ZNC
Official Full Name
cytochrome c oxidase assembly factor COX14provided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-626
See related
AllianceGenome:ZFIN:ZDB-GENE-060503-626
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-222f2.8
Summary
Predicted to be located in mitochondrial membrane. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 10. Orthologous to human COX14 (cytochrome c oxidase assembly factor COX14). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See cox14 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (5752257..5756384)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (5722411..5726538)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene si:dkey-222f2.1 Neighboring gene BCDIN3 domain containing Neighboring gene ceramide synthase 5 Neighboring gene uncharacterized LOC103909525 Neighboring gene uncharacterized LOC103909524

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. CCN6 influences transcription and controls mitochondrial mass and muscle organization. Ganguly A, et al. FASEB J, 2023 Mar. PMID 36794678
  2. Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation. Mueller RL, et al. BMC Genomics, 2010 Sep 9. PMID 20828405, Free PMC Article
  3. Zebrafish cox17 modulates primitive erythropoiesis via regulation of mitochondrial metabolism to facilitate hypoxia tolerance. Li L, et al. FASEB J, 2022 Nov. PMID 36208295
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome c oxidase assembly protein COX14 homolog
Names
COX14 cytochrome c oxidase assembly factor
cytochrome c oxidase assembly homolog 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001302766.1 → NP_001289695.1  cytochrome c oxidase assembly protein COX14 homolog

    See identical proteins and their annotated locations for NP_001289695.1

    Status: VALIDATED

    Source sequence(s)
    EH557256
    UniProtKB/Swiss-Prot
    A8E7D3
    Conserved Domains (1) summary
    pfam14880
    Location:1 → 51
    COX14; Cytochrome oxidase c assembly

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    5752257..5756384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8E7D3.2 GenPept UniProtKB/Swiss-Prot:A8E7D3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.