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abhd10a abhydrolase domain containing 10, depalmitoylase a [ Danio rerio (zebrafish) ]

Gene ID: 568517, updated on 4-Jan-2025

Summary

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Official Symbol
abhd10aprovided by ZNC
Official Full Name
abhydrolase domain containing 10, depalmitoylase aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060526-144
See related
Ensembl:ENSDARG00000076435 AllianceGenome:ZFIN:ZDB-GENE-060526-144
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
abhd10; fb10b08; wu:fb10b08; si:ch211-271b14.3
Summary
Predicted to enable mycophenolic acid acyl-glucuronide esterase activity and palmitoyl-(protein) hydrolase activity. Predicted to be located in membrane and mitochondrion. Orthologous to human ABHD10 (abhydrolase domain containing 10, depalmitoylase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See abhd10a in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (67884083..67895834, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (67209046..67218142, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene zgc:152816 Neighboring gene transgelin 3a Neighboring gene GS homeobox 1 Neighboring gene mitochondrial translational initiation factor 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables mycophenolic acid acyl-glucuronide esterase activity IEA
Inferred from Electronic Annotation
more info
  
enables palmitoyl-(protein) hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
abhydrolase domain containing 10, depalmitoylase a
Names
abhydrolase domain containing 10a
NP_001313452.1
NP_001313453.1
XP_005165696.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001326523.1 → NP_001313452.1  abhydrolase domain containing 10, depalmitoylase a isoform 1

    Status: VALIDATED

    Source sequence(s)
    CU861887
    UniProtKB/TrEMBL
    A0A0R4ILM1, A0A8M1P930
    Related
    ENSDARP00000136531.1, ENSDART00000158917.3
    Conserved Domains (2) summary
    COG0596
    Location:44 → 256
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
    pfam12695
    Location:56 → 258
    Abhydrolase_5; Alpha/beta hydrolase family

  2. NM_001326524.1 → NP_001313453.1  abhydrolase domain containing 10, depalmitoylase a isoform 2

    Status: VALIDATED

    Source sequence(s)
    CU861887
    UniProtKB/TrEMBL
    A0A8M1P818
    Related
    ENSDART00000169254.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    67884083..67895834 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005165639.5 → XP_005165696.1  abhydrolase domain containing 10, depalmitoylase a isoform X1

    UniProtKB/TrEMBL
    A0A8M2BCX5
    Conserved Domains (2) summary
    COG0596
    Location:46 → 258
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
    pfam12695
    Location:58 → 260
    Abhydrolase_5; Alpha/beta hydrolase family
Nucleotide Protein
Heading Accession and Version

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