afp4 antifreeze protein type IV [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: afp4provided by ZNC
Official Full Name: antifreeze protein type IVprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5217
See related: Ensembl:ENSDARG00000095863 AllianceGenome:ZFIN:ZDB-GENE-030131-5217
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa18f02; fb64g03; wu:fa18f02; wu:fb64g03; zgc:161979
Summary: Predicted to enable lipid binding activity. Acts upstream of or within dorsal convergence and epiboly. Predicted to be located in extracellular region. Is expressed in gut; intestinal bulb; intestine; liver; and yolk syncytial layer. Orthologous to human APOA2 (apolipoprotein A2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 16

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (45914480..45917269, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (45947764..45950541, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AA605743 (e-PCR)
- UniSTS:205401

fb64g03 (e-PCR), detects polymorphism
- UniSTS:189058

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables lipid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within dorsal convergence	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within epiboly	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within lipid transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipoprotein metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: antifreeze protein type IV

Names: afp4a; afp4b; type IV antifreeze protein A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.