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ckap2l cytoskeleton associated protein 2-like [ Danio rerio (zebrafish) ]

Gene ID: 569937, updated on 4-Jan-2025

Summary

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Official Symbol
ckap2lprovided by ZNC
Official Full Name
cytoskeleton associated protein 2-likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6690
See related
Ensembl:ENSDARG00000100573 AllianceGenome:ZFIN:ZDB-GENE-030131-6690
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa02g08; wu:fa02g08; si:ch211-230g14.4; si:ch211-255a21.1
Summary
Predicted to be located in cytoplasm. Predicted to be active in centrosome; cytosol; and mitotic spindle. Human ortholog(s) of this gene implicated in Filippi syndrome. Orthologous to human CKAP2L (cytoskeleton associated protein 2 like). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See ckap2l in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (13549586..13561074)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (13049391..13060852)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene SEC14-like lipid binding 8 Neighboring gene novel protein similar to human and mouse cyclin M4 (CNNM4) Neighboring gene uncharacterized LOC101885304 Neighboring gene si:ch211-230g14.3 Neighboring gene uncharacterized LOC101885516

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes. Gui H, et al. Genome Biol, 2017 Mar 8. PMID 28274275, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitotic spindle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cytoskeleton-associated protein 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126431.2 → NP_001119903.2  cytoskeleton-associated protein 2-like

    Status: VALIDATED

    Source sequence(s)
    AL954191
    UniProtKB/TrEMBL
    A2BG40
    Related
    ENSDARP00000139380.1, ENSDART00000171270.2
    Conserved Domains (1) summary
    pfam15297
    Location:446 → 761
    CKAP2_C; Cytoskeleton-associated protein 2 C-terminus

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    13549586..13561074
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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