aasdh aminoadipate-semialdehyde dehydrogenase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: aasdhprovided by ZNC
Official Full Name: aminoadipate-semialdehyde dehydrogenaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041210-322
See related: Ensembl:ENSDARG00000022730 AllianceGenome:ZFIN:ZDB-GENE-041210-322
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkeyp-117h8.3
Summary: Predicted to enable acid-thiol ligase activity. Predicted to be involved in amino acid activation for nonribosomal peptide biosynthetic process and fatty acid metabolic process. Predicted to act upstream of or within lipid metabolic process. Orthologous to human AASDH (aminoadipate-semialdehyde dehydrogenase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (25645490..25659368)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (25746390..25760230)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables acid-thiol ligase activity	IEA Inferred from Electronic Annotation more info
enables acid-thiol ligase activity	ISS Inferred from Sequence or Structural Similarity more info
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in amino acid activation for nonribosomal peptide biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within fatty acid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in fatty acid metabolic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: beta-alanine-activating enzyme

Names: acyl-CoA synthetase family member 4

NP_001410730.1

EC 6.2.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.