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chordc1a cysteine and histidine-rich domain (CHORD) containing 1a [ Danio rerio (zebrafish) ]

Gene ID: 573996, updated on 2-Nov-2024

Summary

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Official Symbol
chordc1aprovided by ZNC
Official Full Name
cysteine and histidine-rich domain (CHORD) containing 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050626-79
See related
Ensembl:ENSDARG00000003973 AllianceGenome:ZFIN:ZDB-GENE-050626-79
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:114108
Summary
Predicted to enable zinc ion binding activity. Predicted to be involved in centrosome duplication. Orthologous to human CHORDC1 (cysteine and histidine rich domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See chordc1a in Genome Data Viewer
Location:
chromosome: 15
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (43961827..43977980, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (43938384..43954537, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101885254 Neighboring gene uncharacterized LOC103908875 Neighboring gene NLR family, CARD domain containing 3-like Neighboring gene nuclear mitotic apparatus protein 1-like Neighboring gene small Cajal body-specific RNA 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Nox4 promotes osteoblast differentiation through TGF-beta signal pathway. Cao Z, et al. Free Radic Biol Med, 2022 Nov 20. PMID 36372285
  2. Rab32 and Rab38 genes in chordate pigmentation: an evolutionary perspective. Coppola U, et al. BMC Evol Biol, 2016 Jan 27. PMID 26818140, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in centrosome duplication IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
cysteine and histidine-rich domain-containing protein 1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025175.1 → NP_001020346.1  cysteine and histidine-rich domain-containing protein 1a

    See identical proteins and their annotated locations for NP_001020346.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097168
    UniProtKB/TrEMBL
    A0A8M1N6Z6, F1QHZ7, Q4QRD9
    Related
    ENSDARP00000041248.6, ENSDART00000041249.9
    Conserved Domains (2) summary
    cd06488
    Location:231 → 317
    p23_melusin_like; p23_like domain similar to the C-terminal (tail) domain of vertebrate Melusin and related proteins. Melusin's tail domain interacts with the cytoplasmic domain of beta1-A and beta1-D isoforms of beta1 integrin, it does not bind other integrin beta ...
    pfam04968
    Location:3 → 64
    CHORD; CHORD

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    43961827..43977980 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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