notch2 - notch receptor 2
Predicted to enable Notch binding activity. Acts upstream of or within several processes, including face morphogenesis; lymphangiogenesis; and pancreas regeneration. Predicted to be located in nucleus and plasma membrane. Predicted to be part of receptor complex. Is expressed in several structures, including digestive system; mesoderm; nervous system; pectoral fin; and splanchnocranium. Human ortholog(s) of this gene implicated in Alagille syndrome and Hajdu-Cheney syndrome. Orthologous to human NOTCH2 (notch receptor 2). [provided by Alliance of Genome Resources, Oct 2024]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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