HCN2 - hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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