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Vmn2r85 vomeronasal 2, receptor 85 [ Mus musculus (house mouse) ]

Gene ID: 623734, updated on 9-Dec-2024

Summary

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Official Symbol
Vmn2r85provided by MGI
Official Full Name
vomeronasal 2, receptor 85provided by MGI
Primary source
MGI:MGI:3646965
See related
Ensembl:ENSMUSG00000092048 AllianceGenome:MGI:3646965
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG623734
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Vmn2r85 in Genome Data Viewer
Location:
10 D3; 10 77.9 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (130253658..130266615, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (130418261..130429612, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor 84 Neighboring gene CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, pseudogene Neighboring gene STARR-seq mESC enhancer starr_28334 Neighboring gene opioid growth factor receptor-like 1 pseudogene Neighboring gene vomeronasal 2, receptor 86

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal 2, receptor 85
Names
vomeronasal 2 receptor Vmn2r85

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102602.1 → NP_001096072.1  vomeronasal 2, receptor 85 precursor

    See identical proteins and their annotated locations for NP_001096072.1

    Status: PROVISIONAL

    Source sequence(s)
    AC159473
    Consensus CDS
    CCDS48736.1
    UniProtKB/TrEMBL
    A0A3B2WBK8, G3UW56
    Related
    ENSMUSP00000128792.3, ENSMUST00000171811.4
    Conserved Domains (3) summary
    cd06365
    Location:41 → 500
    PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam00003
    Location:596 → 831
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam07562
    Location:509 → 561
    NCD3G; Nine Cysteines Domain of family 3 GPCR

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    130253658..130266615 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155907.1 → XP_036011800.1  vomeronasal 2, receptor 85 isoform X1

    Conserved Domains (3) summary
    cd15283
    Location:313 → 565
    7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:240 → 293
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:150 → 232
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

  2. XM_036155908.1 → XP_036011801.1  vomeronasal 2, receptor 85 isoform X2

    UniProtKB/TrEMBL
    A0A3B2WBK8
    Conserved Domains (3) summary
    cd15283
    Location:581 → 833
    7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06365
    Location:46 → 500
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam07562
    Location:508 → 561
    NCD3G; Nine Cysteines Domain of family 3 GPCR
Nucleotide Protein Strain
Heading Accession and Version

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