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sh3d21 SH3 domain containing 21 [ Danio rerio (zebrafish) ]

Gene ID: 641492, updated on 14-Nov-2024

Summary

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Official Symbol
sh3d21provided by ZNC
Official Full Name
SH3 domain containing 21provided by ZNC
Primary source
ZFIN:ZDB-GENE-051120-57
See related
Ensembl:ENSDARG00000099448 AllianceGenome:ZFIN:ZDB-GENE-051120-57
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:123285
Summary
Predicted to be involved in actin filament organization and cell migration. Is expressed in corneal epithelium. Orthologous to human SH3D21 (SH3 domain containing 21). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See sh3d21 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (35905031..35938157)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (35952136..35985282)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487938 Neighboring gene thyroid hormone receptor associated protein 3a Neighboring gene eva-1 homolog Ba (C. elegans) Neighboring gene serine/threonine kinase 40

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber. Takamiya M, et al. PLoS One, 2015. PMID 25692557, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC123285

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
SH3 domain-containing protein 21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037432.2 → NP_001032509.2  SH3 domain-containing protein 21

    Status: VALIDATED

    Source sequence(s)
    BX321921
    UniProtKB/TrEMBL
    A0A0R4IK14, A0A8M1N8B2
    Related
    ENSDARP00000135563.1, ENSDART00000162411.2
    Conserved Domains (4) summary
    cd11873
    Location:2 → 55
    SH3_CD2AP-like_1; First Src Homology 3 domain (SH3A) of CD2-associated protein and similar proteins
    cd11874
    Location:83 → 135
    SH3_CD2AP-like_2; Second Src Homology 3 domain (SH3B) of CD2-associated protein and similar proteins
    cd12142
    Location:177 → 231
    SH3_D21-like; Src Homology 3 domain of SH3 domain-containing protein 21 (SH3D21) and similar proteins
    pfam09798
    Location:377 → 411
    LCD1; DNA damage checkpoint protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    35905031..35938157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158311.5 → XP_005158368.1  SH3 domain-containing protein 21 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B585
    Conserved Domains (5) summary
    cd11873
    Location:2 → 55
    SH3_CD2AP-like_1; First Src Homology 3 domain (SH3A) of CD2-associated protein and similar proteins
    cd11874
    Location:83 → 135
    SH3_CD2AP-like_2; Second Src Homology 3 domain (SH3B) of CD2-associated protein and similar proteins
    cd12142
    Location:177 → 231
    SH3_D21-like; Src Homology 3 domain of SH3 domain-containing protein 21 (SH3D21) and similar proteins
    pfam09798
    Location:449 → 483
    LCD1; DNA damage checkpoint protein
    pfam10267
    Location:407 → 494
    Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein

  2. XM_005158312.5 → XP_005158369.1  SH3 domain-containing protein 21 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B567
    Conserved Domains (5) summary
    cd11873
    Location:2 → 55
    SH3_CD2AP-like_1; First Src Homology 3 domain (SH3A) of CD2-associated protein and similar proteins
    cd11874
    Location:83 → 135
    SH3_CD2AP-like_2; Second Src Homology 3 domain (SH3B) of CD2-associated protein and similar proteins
    cd12142
    Location:177 → 231
    SH3_D21-like; Src Homology 3 domain of SH3 domain-containing protein 21 (SH3D21) and similar proteins
    pfam09798
    Location:426 → 460
    LCD1; DNA damage checkpoint protein
    pfam10267
    Location:357 → 471
    Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein

  3. XM_005158313.5 → XP_005158370.1  SH3 domain-containing protein 21 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B4P5
    Conserved Domains (5) summary
    cd11873
    Location:2 → 55
    SH3_CD2AP-like_1; First Src Homology 3 domain (SH3A) of CD2-associated protein and similar proteins
    cd11874
    Location:83 → 135
    SH3_CD2AP-like_2; Second Src Homology 3 domain (SH3B) of CD2-associated protein and similar proteins
    cd12142
    Location:177 → 231
    SH3_D21-like; Src Homology 3 domain of SH3 domain-containing protein 21 (SH3D21) and similar proteins
    pfam09798
    Location:400 → 434
    LCD1; DNA damage checkpoint protein
    pfam10267
    Location:358 → 445
    Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein
Nucleotide Protein
Heading Accession and Version

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