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SEMA4A semaphorin 4A [ Homo sapiens (human) ]

Gene ID: 64218, updated on 27-Dec-2024

Summary

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Official Symbol
SEMA4Aprovided by HGNC
Official Full Name
semaphorin 4Aprovided by HGNC
Primary source
HGNC:HGNC:10729
See related
Ensembl:ENSG00000196189 MIM:607292; AllianceGenome:HGNC:10729
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RP35; SEMB; SEMAB; CORD10
Summary
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
Expression
Broad expression in skin (RPKM 12.9), lymph node (RPKM 12.8) and 20 other tissues See more
Orthologs
mouse all
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Genomic context

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See SEMA4A in Genome Data Viewer
Location:
1q22
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (156147373..156177744)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (155285786..155316193)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (156119735..156147535)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr1:156045982-156046889 and GRCh37_chr1:156046890-156047796 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:156051244-156052056 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:156052057-156052870 Neighboring gene mex-3 RNA binding family member A Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:156056191-156057025 Neighboring gene Sharpr-MPRA regulatory region 15377 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1838 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156067261-156068134 Neighboring gene lamin A/C Neighboring gene VISTA enhancer hs2129 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156077037-156077778 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1420 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1421 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156087275-156087774 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156090429-156091415 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156093390-156094377 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1843 Neighboring gene Sharpr-MPRA regulatory region 4592 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1845 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156096352-156097337 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1846 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr1:156099693-156100892 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1847 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1848 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1849 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1850 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:156131887-156132038 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156146693-156147195 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156149713-156150215 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156151223-156151726 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:156151727-156152229 Neighboring gene uncharacterized LOC124900449 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1851 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1852 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1853 Neighboring gene solute carrier family 25 member 44

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. T-cell specific upregulation of Sema4A as risk factor for autoimmunity in systemic lupus erythematosus and rheumatoid arthritis. Cavalcanti CAJ, et al. Autoimmunity, 2020 Mar. PMID 31876207
  2. Doxorubicin-induced epithelial-mesenchymal transition through SEMA 4A in hepatocellular carcinoma. Pan JX, et al. Biochem Biophys Res Commun, 2016 Oct 28. PMID 27697528
  3. On variants and disease-causing mutations: Case studies of a SEMA4A variant identified in inherited blindness. Bryant L, et al. Ophthalmic Genet, 2018 Jan-Feb. PMID 28805479, Free PMC Article
  4. Expression of Semaphorin 4A and its potential role in rheumatoid arthritis. Wang L, et al. Arthritis Res Ther, 2015 Aug 25. PMID 26303122, Free PMC Article
  5. Sema4A Responds to Hypoxia and Is Involved in Breast Cancer Progression. Liu X, et al. Biol Pharm Bull, 2018 Dec 1. PMID 30270262

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Semaphorin 4A Maintains Trophoblastic Function via Activating the STAT3 Pathway.
    Title: Semaphorin 4A Maintains Trophoblastic Function via Activating the STAT3 Pathway.
  2. Semaphorin4A promotes lung cancer by activation of NF-kappaB pathway mediated by PlexinB1.
    Title: Semaphorin4A promotes lung cancer by activation of NF-κB pathway mediated by PlexinB1.
  3. Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8[+] T cell cytotoxicity and proliferation.
    Title: Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8(+) T cell cytotoxicity and proliferation.
  4. The possible involvement of sema3A and sema4A in the pathogenesis of multiple sclerosis.
    Title: The possible involvement of sema3A and sema4A in the pathogenesis of multiple sclerosis.
  5. Identifying Function Determining Residues in Neuroimmune Semaphorin 4A.
    Title: Identifying Function Determining Residues in Neuroimmune Semaphorin 4A.
  6. Semaphorin 4A restricts tumor progression by inhibiting angiogenesis of oral squamous cell carcinoma cells.
    Title: Semaphorin 4A restricts tumor progression by inhibiting angiogenesis of oral squamous cell carcinoma cells.
  7. Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner.
    Title: Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner.
  8. T-cell specific upregulation of Sema4A as risk factor for autoimmunity in systemic lupus erythematosus and rheumatoid arthritis.
    Title: T-cell specific upregulation of Sema4A as risk factor for autoimmunity in systemic lupus erythematosus and rheumatoid arthritis.
  9. Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase.
    Title: Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase.
  10. Sema4D and 4A seem to play a critical role in the pathogenesis of some autoimmune diseases, such as multiple sclerosis.
    Title: Semaphorin 4A, 4C, and 4D: Function comparison in the autoimmunity, allergy, and cancer.
Submit: New GeneRIF Correction See all GeneRIFs (33)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Cone-rod dystrophy 10
MedGen: C1846529 OMIM: 610283 GeneReviews: Not available
Compare labs
Retinitis pigmentosa 35
MedGen: C1853214 OMIM: 610282 GeneReviews: Nonsyndromic Retinitis Pigmentosa Overview
Compare labs

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

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Replication interactions

Interaction Pubs
HIV-1 infection (VSV-G pseudotyped) of CEMT4 T cells downregulates plasma membrane expression of SEMA4A PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ12287

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables chemorepellent activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables neuropilin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables semaphorin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in T-helper 1 cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in neural crest cell migration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of excitatory synapse assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of inhibitory synapse assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of endothelial cell migration IEA
Inferred from Electronic Annotation
more info
  
involved_in semaphorin-plexin signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
semaphorin-4A
Names
sema B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
semaphorin-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_027683.1 RefSeqGene

    Range
    8642..32801
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001193300.2 → NP_001180229.1  semaphorin-4A isoform 1 precursor

    See identical proteins and their annotated locations for NP_001180229.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, as compared to variant 1. Variants 1-3 encode the same isoform (1).
    Source sequence(s)
    AL135927
    Consensus CDS
    CCDS1132.1
    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5
    Conserved Domains (3) summary
    cd11256
    Location:55 → 495
    Sema_4A; The Sema domain, a protein interacting module, of semaphorin 4A (Sema4A)
    smart00423
    Location:496 → 541
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:566 → 638
    Ig; Immunoglobulin domain

  2. NM_001193301.2 → NP_001180230.1  semaphorin-4A isoform 1 precursor

    See identical proteins and their annotated locations for NP_001180230.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) has an alternate 5' UTR, as compared to variant 1. Variants 1-3 encode the same isoform (1).
    Source sequence(s)
    AY358531
    Consensus CDS
    CCDS1132.1
    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5
    Related
    ENSP00000347117.2, ENST00000355014.6
    Conserved Domains (3) summary
    cd11256
    Location:55 → 495
    Sema_4A; The Sema domain, a protein interacting module, of semaphorin 4A (Sema4A)
    smart00423
    Location:496 → 541
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:566 → 638
    Ig; Immunoglobulin domain

  3. NM_001193302.2 → NP_001180231.1  semaphorin-4A isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks two internal exons in 5' different regions respectively, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) is shorter at the N-terminus and lacks an internal segment, as compared to isoform 1.
    Source sequence(s)
    AK091127, AY358531
    Consensus CDS
    CCDS53378.1
    UniProtKB/TrEMBL
    Q5TCJ5
    Related
    ENSP00000357267.1, ENST00000368284.5
    Conserved Domains (3) summary
    pfam01437
    Location:364 → 408
    PSI; Plexin repeat
    cl11960
    Location:434 → 506
    Ig; Immunoglobulin domain
    cl15693
    Location:1 → 363
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

  4. NM_001370567.1 → NP_001357496.1  semaphorin-4A isoform 1 precursor

    Status: REVIEWED

    Source sequence(s)
    AL135927
    Consensus CDS
    CCDS1132.1
    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5
    Related
    ENSP00000357265.1, ENST00000368282.1
    Conserved Domains (3) summary
    cd11256
    Location:55 → 495
    Sema_4A; The Sema domain, a protein interacting module, of semaphorin 4A (Sema4A)
    smart00423
    Location:496 → 541
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:566 → 638
    Ig; Immunoglobulin domain

  5. NM_001370568.1 → NP_001357497.1  semaphorin-4A isoform 3

    Status: REVIEWED

    Source sequence(s)
    AL135927
    UniProtKB/TrEMBL
    B4DKS5, Q5TCJ5
    Conserved Domains (3) summary
    smart00423
    Location:397 → 442
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:467 → 539
    Ig; Immunoglobulin domain
    cl15693
    Location:1 → 396
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

  6. NM_001370569.1 → NP_001357498.1  semaphorin-4A isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL135927
    UniProtKB/TrEMBL
    Q5TCJ5
    Conserved Domains (3) summary
    smart00423
    Location:327 → 372
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:397 → 469
    Ig; Immunoglobulin domain
    cl15693
    Location:1 → 326
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

  7. NM_001370571.1 → NP_001357500.1  semaphorin-4A isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL135927
    UniProtKB/TrEMBL
    Q5TCJ5
    Conserved Domains (3) summary
    smart00423
    Location:327 → 372
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:397 → 469
    Ig; Immunoglobulin domain
    cl15693
    Location:1 → 326
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

  8. NM_022367.4 → NP_071762.2  semaphorin-4A isoform 1 precursor

    See identical proteins and their annotated locations for NP_071762.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) is the longest transcript. Variants 1-3 encode the same isoform (1).
    Source sequence(s)
    AY358531, BC020974, DA409501
    Consensus CDS
    CCDS1132.1
    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5
    Related
    ENSP00000357268.3, ENST00000368285.8
    Conserved Domains (3) summary
    cd11256
    Location:55 → 495
    Sema_4A; The Sema domain, a protein interacting module, of semaphorin 4A (Sema4A)
    smart00423
    Location:496 → 541
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:566 → 638
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    156147373..156177744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047427664.1 → XP_047283620.1  semaphorin-4A isoform X2

    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5

  2. XM_047427677.1 → XP_047283633.1  semaphorin-4A isoform X3

    UniProtKB/TrEMBL
    B4DKS5, Q5TCJ5

  3. XM_011509878.3 → XP_011508180.1  semaphorin-4A isoform X3

    See identical proteins and their annotated locations for XP_011508180.1

    UniProtKB/TrEMBL
    B4DKS5, Q5TCJ5
    Conserved Domains (3) summary
    smart00423
    Location:397 → 442
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:467 → 539
    Ig; Immunoglobulin domain
    cl15693
    Location:1 → 396
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

  4. XM_011509871.4 → XP_011508173.1  semaphorin-4A isoform X1

    UniProtKB/TrEMBL
    Q5TCJ5
    Conserved Domains (3) summary
    cd11256
    Location:17 → 457
    Sema_4A; The Sema domain, a protein interacting module, of semaphorin 4A (Sema4A)
    pfam01437
    Location:458 → 502
    PSI; Plexin repeat
    cl11960
    Location:528 → 600
    Ig; Immunoglobulin domain

  5. XM_047427678.1 → XP_047283634.1  semaphorin-4A isoform X4

    Related
    ENST00000487358.5

  6. XM_047427670.1 → XP_047283626.1  semaphorin-4A isoform X2

    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5

  7. XM_047427671.1 → XP_047283627.1  semaphorin-4A isoform X2

    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5

  8. XM_011509872.3 → XP_011508174.1  semaphorin-4A isoform X2

    See identical proteins and their annotated locations for XP_011508174.1

    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5
    Conserved Domains (3) summary
    cd11256
    Location:55 → 495
    Sema_4A; The Sema domain, a protein interacting module, of semaphorin 4A (Sema4A)
    smart00423
    Location:496 → 541
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:566 → 638
    Ig; Immunoglobulin domain

  9. XM_011509874.3 → XP_011508176.1  semaphorin-4A isoform X3

    See identical proteins and their annotated locations for XP_011508176.1

    UniProtKB/TrEMBL
    B4DKS5, Q5TCJ5
    Conserved Domains (3) summary
    smart00423
    Location:397 → 442
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:467 → 539
    Ig; Immunoglobulin domain
    cl15693
    Location:1 → 396
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

  10. XM_011509875.4 → XP_011508177.1  semaphorin-4A isoform X3

    See identical proteins and their annotated locations for XP_011508177.1

    UniProtKB/TrEMBL
    B4DKS5, Q5TCJ5
    Conserved Domains (3) summary
    smart00423
    Location:397 → 442
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:467 → 539
    Ig; Immunoglobulin domain
    cl15693
    Location:1 → 396
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    155285786..155316193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054338170.1 → XP_054194145.1  semaphorin-4A isoform X2

    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5

  2. XM_054338167.1 → XP_054194142.1  semaphorin-4A isoform X5

    UniProtKB/TrEMBL
    Q5TCJ5

  3. XM_054338176.1 → XP_054194151.1  semaphorin-4A isoform X6

  4. XM_054338175.1 → XP_054194150.1  semaphorin-4A isoform X3

    UniProtKB/TrEMBL
    B4DKS5, Q5TCJ5

  5. XM_054338171.1 → XP_054194146.1  semaphorin-4A isoform X2

    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5

  6. XM_054338172.1 → XP_054194147.1  semaphorin-4A isoform X2

    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5

  7. XM_054338168.1 → XP_054194143.1  semaphorin-4A isoform X2

    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5

  8. XM_054338169.1 → XP_054194144.1  semaphorin-4A isoform X2

    UniProtKB/Swiss-Prot
    B2RDH8, B3KR76, Q5TCI5, Q5TCJ6, Q8WUA9, Q9H3S1
    UniProtKB/TrEMBL
    Q5TCJ5

  9. XM_054338173.1 → XP_054194148.1  semaphorin-4A isoform X3

    UniProtKB/TrEMBL
    B4DKS5, Q5TCJ5

  10. XM_054338174.1 → XP_054194149.1  semaphorin-4A isoform X3

    UniProtKB/TrEMBL
    B4DKS5, Q5TCJ5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9H3S1.2 GenPept UniProtKB/Swiss-Prot:Q9H3S1

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