U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rpn2 ribophorin II [ Rattus norvegicus (Norway rat) ]

Gene ID: 64701, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Rpn2provided by RGD
Official Full Name
ribophorin IIprovided by RGD
Primary source
RGD:62075
See related
EnsemblRapid:ENSRNOG00000007492 AllianceGenome:RGD:62075
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables ribosome binding activity. Involved in response to xenobiotic stimulus. Located in autophagosome membrane. Orthologous to human RPN2 (ribophorin II). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 983.5), Kidney (RPKM 788.4) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Rpn2 in Genome Data Viewer
Location:
3q42
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (166361955..166409272)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (145941787..145989271)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (153398373..153445633)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene RB transcriptional corepressor like 1 Neighboring gene 60S ribosomal protein L34 pseudogene Neighboring gene uncharacterized LOC134486195 Neighboring gene U7 small nuclear RNA Neighboring gene maestro heat-like repeat family member 8 Neighboring gene uncharacterized LOC134486194 Neighboring gene growth hormone releasing hormone Neighboring gene mannosidase beta like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Proteins of rough microsomal membranes related to ribosome binding. II. Cross-linking of bound ribosomes to specific membrane proteins exposed at the binding sites. Kreibich G, et al. J Cell Biol, 1978 May. PMID 418074, Free PMC Article
  2. Studies on the mechanisms of autophagy: formation of the autophagic vacuole. Dunn WA Jr. J Cell Biol, 1990 Jun. PMID 2351689, Free PMC Article
  3. Novel flutamide regulated genes in the rat ventral prostate: differential modulation of their expression by castration and flutamide treatments. Limaye AM, et al. Asian J Androl, 2007 Nov. PMID 17968466
  4. Localization of ribophorin II to the endoplasmic reticulum involves both its transmembrane and cytoplasmic domains. Fu J, et al. Eur J Cell Biol, 2000 Apr. PMID 10826490, Free PMC Article
  5. Age-associated changes in histology and gene-expression profile in the rat ventral prostate. Lau KM, et al. Lab Invest, 2003 May. PMID 12746483

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ribosome binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein N-linked glycosylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein N-linked glycosylation ISO
Inferred from Sequence Orthology
more info
  
involved_in protein N-linked glycosylation ISO
Inferred from Sequence Orthology
more info
  
involved_in protein glycosylation ISO
Inferred from Sequence Orthology
more info
  
involved_in response to xenobiotic stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in autophagosome membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear body IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
  
part_of oligosaccharyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of oligosaccharyltransferase complex IEA
Inferred from Electronic Annotation
more info
  
part_of oligosaccharyltransferase complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
Names
RPN-II
dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit
ribophorin-2
NP_113886.1
XP_006235441.1
XP_038961743.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031698.1 → NP_113886.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor

    See identical proteins and their annotated locations for NP_113886.1

    Status: PROVISIONAL

    Source sequence(s)
    X55298
    UniProtKB/Swiss-Prot
    P25235, Q6P9X0
    UniProtKB/TrEMBL
    A6JWR7
    Related
    ENSRNOP00000076455.1, ENSRNOT00000118622.2
    Conserved Domains (1) summary
    pfam05817
    Location:9 → 623
    Ribophorin_II; Oligosaccharyltransferase subunit Ribophorin II

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    166361955..166409272
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006235379.4 → XP_006235441.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform X1

    UniProtKB/Swiss-Prot
    P25235, Q6P9X0
    UniProtKB/TrEMBL
    A0A8L2QVV5, A6JWR7
    Related
    ENSRNOP00000063207.2, ENSRNOT00000068135.4
    Conserved Domains (1) summary
    pfam05817
    Location:9 → 623
    Ribophorin_II; Oligosaccharyltransferase subunit Ribophorin II

  2. XM_039105815.1 → XP_038961743.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform X2

    UniProtKB/TrEMBL
    A6JWR9
    Conserved Domains (1) summary
    pfam05817
    Location:2 → 406
    Ribophorin_II; Oligosaccharyltransferase subunit Ribophorin II
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25235.2 GenPept UniProtKB/Swiss-Prot:P25235

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools