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AGAP7P ArfGAP with GTPase domain, ankyrin repeat and PH domain 7, pseudogene [ Homo sapiens (human) ]

Gene ID: 653268, updated on 10-Dec-2024

Summary

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Official Symbol
AGAP7Pprovided by HGNC
Official Full Name
ArfGAP with GTPase domain, ankyrin repeat and PH domain 7, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:23465
See related
Ensembl:ENSG00000299595 AllianceGenome:HGNC:23465
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AGAP7; AGAP-7; CTGLF4; bA109G10.1
Summary
Predicted to enable GTPase activator activity and GTPase activity. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in testis (RPKM 14.9), prostate (RPKM 10.4) and 25 other tissues See more
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Genomic context

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See AGAP7P in Genome Data Viewer
Location:
10q11.22
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (46109495..46131678)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (46990372..47012555)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (51464144..51486327, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378287 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:51551103-51551604 Neighboring gene Sharpr-MPRA regulatory region 2638 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:51541582-51542406 Neighboring gene microseminoprotein beta Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:51528729-51529229 Neighboring gene ribosomal protein L23a pseudogene 61 Neighboring gene Sharpr-MPRA regulatory region 10026 Neighboring gene Sharpr-MPRA regulatory regions 2667 and 7132 Neighboring gene uncharacterized LOC124902418 Neighboring gene ANTXR like pseudogene 1 Neighboring gene adenosylhomocysteinase pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. Adams MD, et al. Nature, 1995 Sep 28. PMID 7566098
  2. The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. Katsogiannou M, et al. Mol Cell Proteomics, 2014 Dec. PMID 25277244, Free PMC Article
  3. New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing. Basei FL, et al. Proteome Sci, 2015. PMID 25798074, Free PMC Article
  4. Protein interactome reveals converging molecular pathways among autism disorders. Sakai Y, et al. Sci Transl Med, 2011 Jun 8. PMID 21653829, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7 pseudogene
  • centaurin, gamma-like family, member 4
  • putative Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_126580.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AA337655, AL040331, AL589822, AW014387, BY996334
    Related
    ENST00000764944.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    46109495..46131678
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    46990372..47012555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001077685.2: Suppressed sequence

    Description
    NM_001077685.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5VUJ5.1 GenPept UniProtKB/Swiss-Prot:Q5VUJ5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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