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CAPRIN2 caprin family member 2 [ Homo sapiens (human) ]

Gene ID: 65981, updated on 2-Nov-2024

Summary

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Official Symbol
CAPRIN2provided by HGNC
Official Full Name
caprin family member 2provided by HGNC
Primary source
HGNC:HGNC:21259
See related
Ensembl:ENSG00000110888 MIM:610375; AllianceGenome:HGNC:21259
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EEG1; EEG-1; C1QDC1; RNG140
Summary
The protein encoded by this gene may regulate the transport of mRNA. It may play a role in the differentiation of erythroblasts. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Expression
Ubiquitous expression in testis (RPKM 12.6), brain (RPKM 7.2) and 25 other tissues See more
Orthologs
mouse all
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Genomic context

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See CAPRIN2 in Genome Data Viewer
Location:
12p11.21
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (30709553..30754951, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (30584217..30698047, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (30862487..30907885, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369719 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_28131 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30756793-30757482 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30757483-30758172 Neighboring gene importin 8 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4321 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6158 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4322 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6159 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:30909210-30909413 Neighboring gene uncharacterized LOC645485 Neighboring gene NANOG hESC enhancer GRCh37_chr12:30938423-30938924 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30945898-30946399 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30946901-30947402 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:30947403-30947902 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30948405-30948904 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30948905-30949406 Neighboring gene long intergenic non-protein coding RNA 941

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Polymorphisms in TRIB2 and CAPRIN2 Genes Contribute to the Susceptibility to High Myopia-Induced Cataract in Han Chinese Population. Ma B, et al. Med Sci Monit, 2023 Jan 30. PMID 36710479, Free PMC Article
  2. Cloning and characterization of a gene expressed during terminal differentiation that encodes a novel inhibitor of growth. Aerbajinai W, et al. J Biol Chem, 2004 Jan 16. PMID 14593112
  3. Upregulated lncRNA Cyclin-dependent kinase inhibitor 2B antisense RNA 1 induces the proliferation and migration of colorectal cancer by miR-378b/CAPRIN2 axis. Zheng Y, et al. Bioengineered, 2021 Dec. PMID 34511033, Free PMC Article
  4. LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β-catenin signaling pathway. Ai Y, et al. J Cell Mol Med, 2020 Sep. PMID 32691935, Free PMC Article
  5. Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling. Miao H, et al. J Biol Chem, 2014 Dec 5. PMID 25331957, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Polymorphisms in TRIB2 and CAPRIN2 Genes Contribute to the Susceptibility to High Myopia-Induced Cataract in Han Chinese Population.
    Title: Polymorphisms in TRIB2 and CAPRIN2 Genes Contribute to the Susceptibility to High Myopia-Induced Cataract in Han Chinese Population.
  2. Upregulated lncRNA Cyclin-dependent kinase inhibitor 2B antisense RNA 1 induces the proliferation and migration of colorectal cancer by miR-378b/CAPRIN2 axis.
    Title: Upregulated lncRNA Cyclin-dependent kinase inhibitor 2B antisense RNA 1 induces the proliferation and migration of colorectal cancer by miR-378b/CAPRIN2 axis.
  3. LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/beta-catenin signaling pathway.
    Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β-catenin signaling pathway.
  4. findings revealed an unrecognized role of Caprin-2 in facilitating LRP5/6 constitutive phosphorylation at G2/M through forming a quaternary complex with CDK14, Cyclin Y, and LRP5/6.
    Title: Activation/Proliferation-associated Protein 2 (Caprin-2) Positively Regulates CDK14/Cyclin Y-mediated Lipoprotein Receptor-related Protein 5 and 6 (LRP5/6) Constitutive Phosphorylation.
  5. Caprin-2 C1q-related domain forms a flexible homotrimer mediated by calcium, and this trimeric assembly is required for the functioning of caprin-2.
    Title: Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling.
  6. Caprin-2 promotes activation of the canonical Wnt signaling pathway by regulating LRP5/6 phosphorylation.
    Title: Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation.
  7. regulated expression of EEG-1 is involved in the orchestrated regulation of growth that occurs as erythroblasts shift from a highly proliferative state toward their terminal phase of differentiation.
    Title: Cloning and characterization of a gene expressed during terminal differentiation that encodes a novel inhibitor of growth.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ11391, FLJ22569, KIAA1873, MGC102894, MGC134847, MGC134848

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in dorsal/ventral axis specification ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of cell growth IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of canonical Wnt signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of canonical Wnt signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of canonical Wnt signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of dendrite morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of dendritic spine morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of receptor complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
caprin-2
Names
C1q domain-containing protein 1
RNA granule protein 140
cytoplasmic activation/proliferation-associated protein 2
gastric cancer multidrug resistance-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029557.2 RefSeqGene

    Range
    4564..49962
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001002259.3 → NP_001002259.1  caprin-2 isoform 1

    See identical proteins and their annotated locations for NP_001002259.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1). This variant is supported by BK001102.1, which is a third party annotation described in PMID:14764709.
    Source sequence(s)
    AC010198, AK021453, AL834212, AY074490, AY074491, BC025420, BQ010043, KF455635
    UniProtKB/Swiss-Prot
    E4NKG2, Q149P6, Q149P7, Q6IMN5, Q6IMN6, Q7Z371, Q8TE70, Q8TE71, Q96RN6, Q9H667, Q9HAL4
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Related
    ENSP00000510623.1, ENST00000687797.1
    Conserved Domains (3) summary
    pfam05483
    Location:88 → 540
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam00386
    Location:999 → 1124
    C1q; C1q domain
    pfam12287
    Location:628 → 929
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  2. NM_001206856.3 → NP_001193785.1  caprin-2 isoform 4

    See identical proteins and their annotated locations for NP_001193785.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the central coding region, and uses an alternate splice site in the 3' coding region that causes a frameshift, compared to variant 1. The encoded isoform (4) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC010198, BC007520, BC117673, BR000870, KF455635
    Consensus CDS
    CCDS55816.1
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Related
    ENSP00000379150.2, ENST00000395805.6
    Conserved Domains (2) summary
    pfam05483
    Location:88 → 510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam12287
    Location:628 → 873
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  3. NM_001319842.2 → NP_001306771.1  caprin-2 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks an exon in the 5' region, initiates translation at a downstream start codon, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (5) has a shorter N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC010198, AY074491, KF455635
    UniProtKB/Swiss-Prot
    Q6IMN6
    Conserved Domains (2) summary
    pfam00386
    Location:665 → 790
    C1q; C1q domain
    pfam12287
    Location:287 → 601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  4. NM_001319843.2 → NP_001306772.1  caprin-2 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) uses an alternate in-frame splice site in the central coding region compared to variant 1. The encoded isoform (6) is shorter than isoform 1. This variant is supported by BK001102.1, which is a third party annotation described in PMID:14764709.
    Source sequence(s)
    AC010198, BK001103, BR000870
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Conserved Domains (3) summary
    pfam05483
    Location:88 → 510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam00386
    Location:998 → 1123
    C1q; C1q domain
    pfam12287
    Location:628 → 928
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  5. NM_001319844.2 → NP_001306773.1  caprin-2 isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at a downstream start codon, and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (7) has a shorter N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Conserved Domains (5) summary
    PTZ00449
    Location:332 → 673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:883 → 1008
    C1q; C1q domain
    pfam12287
    Location:539 → 819
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam13870
    Location:45 → 138
    DUF4201; Domain of unknown function (DUF4201)
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  6. NM_001319845.2 → NP_001306774.1  caprin-2 isoform 8

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (8) has a shorter N-terminus than isoform 1. Variants 8 and 9 encode the same isoform (8).
    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91678.1
    UniProtKB/TrEMBL
    A0A8I5KZC0, A0A8Q3WKF3
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:918 → 1043
    C1q; C1q domain
    pfam12287
    Location:539 → 854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  7. NM_001319846.2 → NP_001306775.1  caprin-2 isoform 8

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (8) has a shorter N-terminus than isoform 1. Variants 8 and 9 encode the same isoform (8).
    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91678.1
    UniProtKB/TrEMBL
    A0A8I5KZC0, A0A8Q3WKF3
    Related
    ENSP00000511879.1, ENST00000695400.1
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:918 → 1043
    C1q; C1q domain
    pfam12287
    Location:539 → 854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  8. NM_001385498.1 → NP_001372427.1  caprin-2 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Conserved Domains (4) summary
    PTZ00121
    Location:130 → 569
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:978 → 1103
    C1q; C1q domain
    pfam12287
    Location:620 → 914
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200 → 315
    Caprin-1_dimer; Caprin-1 dimerization domain

  9. NM_001385499.1 → NP_001372428.1  caprin-2 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Conserved Domains (5) summary
    PTZ00449
    Location:413 → 754
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    COG0419
    Location:76 → 258
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00386
    Location:964 → 1089
    C1q; C1q domain
    pfam12287
    Location:620 → 900
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200 → 315
    Caprin-1_dimer; Caprin-1 dimerization domain

  10. NM_001385500.1 → NP_001372429.1  caprin-2 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Conserved Domains (5) summary
    PTZ00449
    Location:413 → 754
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    COG0419
    Location:76 → 258
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00386
    Location:963 → 1088
    C1q; C1q domain
    pfam12287
    Location:620 → 899
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200 → 315
    Caprin-1_dimer; Caprin-1 dimerization domain

  11. NM_001385501.1 → NP_001372430.1  caprin-2 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91678.1
    UniProtKB/TrEMBL
    A0A8I5KZC0, A0A8Q3WKF3
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:918 → 1043
    C1q; C1q domain
    pfam12287
    Location:539 → 854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  12. NM_001385502.1 → NP_001372431.1  caprin-2 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91677.1
    UniProtKB/TrEMBL
    A0A8Q3WKF3, F5H5J8
    Related
    ENSP00000443353.2, ENST00000542550.6
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:917 → 1042
    C1q; C1q domain
    pfam12287
    Location:539 → 853
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  13. NM_001385503.1 → NP_001372432.1  caprin-2 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91677.1
    UniProtKB/TrEMBL
    A0A8Q3WKF3, F5H5J8
    Related
    ENSP00000511883.1, ENST00000695402.1
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:917 → 1042
    C1q; C1q domain
    pfam12287
    Location:539 → 853
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  14. NM_001385504.1 → NP_001372433.1  caprin-2 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91676.1
    UniProtKB/TrEMBL
    A0A8Q3WKF3, F5GXI7, F5H7T6
    Related
    ENSP00000441005.2, ENST00000540584.2
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:897 → 1022
    C1q; C1q domain
    pfam12287
    Location:539 → 833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  15. NM_001385505.1 → NP_001372434.1  caprin-2 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91676.1
    UniProtKB/TrEMBL
    A0A8Q3WKF3, F5GXI7, F5H7T6
    Related
    ENSP00000511847.1, ENST00000695374.1
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:897 → 1022
    C1q; C1q domain
    pfam12287
    Location:539 → 833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  16. NM_001385506.1 → NP_001372435.1  caprin-2 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91676.1
    UniProtKB/TrEMBL
    A0A8Q3WKF3, F5GXI7, F5H7T6
    Related
    ENSP00000442295.2, ENST00000540436.6
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:897 → 1022
    C1q; C1q domain
    pfam12287
    Location:539 → 833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  17. NM_001385507.1 → NP_001372436.1  caprin-2 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Conserved Domains (5) summary
    PTZ00449
    Location:332 → 673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:883 → 1008
    C1q; C1q domain
    pfam12287
    Location:539 → 819
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam13870
    Location:45 → 138
    DUF4201; Domain of unknown function (DUF4201)
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  18. NM_001385508.1 → NP_001372437.1  caprin-2 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Conserved Domains (5) summary
    PTZ00449
    Location:332 → 673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:882 → 1007
    C1q; C1q domain
    pfam12287
    Location:539 → 818
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam13870
    Location:45 → 138
    DUF4201; Domain of unknown function (DUF4201)
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  19. NM_001385509.1 → NP_001372438.1  caprin-2 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Conserved Domains (5) summary
    PTZ00449
    Location:332 → 673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:882 → 1007
    C1q; C1q domain
    pfam12287
    Location:539 → 818
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam13870
    Location:45 → 138
    DUF4201; Domain of unknown function (DUF4201)
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  20. NM_001385510.1 → NP_001372439.1  caprin-2 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKF3
    Conserved Domains (4) summary
    PTZ00449
    Location:332 → 673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:862 → 987
    C1q; C1q domain
    pfam12287
    Location:539 → 798
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  21. NM_001385511.1 → NP_001372440.1  caprin-2 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3SHV1
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:834 → 959
    C1q; C1q domain
    pfam12287
    Location:539 → 770
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  22. NM_001385512.1 → NP_001372441.1  caprin-2 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3SHV1
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:834 → 959
    C1q; C1q domain
    pfam12287
    Location:539 → 770
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  23. NM_001385513.1 → NP_001372442.1  caprin-2 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3SHV1
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:834 → 959
    C1q; C1q domain
    pfam12287
    Location:539 → 770
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  24. NM_001385514.1 → NP_001372443.1  caprin-2 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91675.1
    UniProtKB/TrEMBL
    A0A8I5KRN0, A0A8Q3SHV1
    Related
    ENSP00000509126.1, ENST00000686317.1
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:833 → 958
    C1q; C1q domain
    pfam12287
    Location:539 → 769
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  25. NM_001385515.1 → NP_001372444.1  caprin-2 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91675.1
    UniProtKB/TrEMBL
    A0A8I5KRN0, A0A8Q3SHV1
    Conserved Domains (4) summary
    PTZ00121
    Location:49 → 488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:833 → 958
    C1q; C1q domain
    pfam12287
    Location:539 → 769
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  26. NM_001385516.1 → NP_001372445.1  caprin-2 isoform 39

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (3) summary
    PTZ00121
    Location:321 → 569
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:620 → 935
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200 → 315
    Caprin-1_dimer; Caprin-1 dimerization domain

  27. NM_001385518.1 → NP_001372447.1  caprin-2 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Related
    ENSP00000511846.1, ENST00000695373.1
    Conserved Domains (3) summary
    PTZ00121
    Location:321 → 569
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:620 → 935
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200 → 315
    Caprin-1_dimer; Caprin-1 dimerization domain

  28. NM_001385519.1 → NP_001372448.1  caprin-2 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (3) summary
    PTZ00121
    Location:240 → 488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539 → 854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  29. NM_001385520.1 → NP_001372449.1  caprin-2 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (3) summary
    PTZ00121
    Location:240 → 488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539 → 854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  30. NM_001385521.1 → NP_001372450.1  caprin-2 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Related
    ENSP00000511564.1, ENST00000694880.1
    Conserved Domains (3) summary
    PTZ00121
    Location:240 → 488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539 → 853
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  31. NM_001385522.1 → NP_001372451.1  caprin-2 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (3) summary
    PTZ00121
    Location:240 → 488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539 → 853
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  32. NM_001385523.1 → NP_001372452.1  caprin-2 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (3) summary
    PTZ00121
    Location:240 → 488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539 → 833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  33. NM_001385524.1 → NP_001372453.1  caprin-2 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Related
    ENSP00000511809.1, ENST00000695328.1
    Conserved Domains (3) summary
    PTZ00121
    Location:240 → 488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539 → 833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  34. NM_001385525.1 → NP_001372454.1  caprin-2 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (3) summary
    PTZ00121
    Location:240 → 488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539 → 833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  35. NM_001385526.1 → NP_001372455.1  caprin-2 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (3) summary
    PTZ00449
    Location:332 → 673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam12287
    Location:539 → 798
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  36. NM_001385527.1 → NP_001372456.1  caprin-2 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (3) summary
    PTZ00121
    Location:240 → 488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539 → 770
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  37. NM_001385528.1 → NP_001372457.1  caprin-2 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Consensus CDS
    CCDS91672.1
    Conserved Domains (2) summary
    pfam00386
    Location:666 → 791
    C1q; C1q domain
    pfam12287
    Location:287 → 602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  38. NM_001385529.1 → NP_001372458.1  caprin-2 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91672.1
    Related
    ENSP00000510181.1, ENST00000684863.1
    Conserved Domains (2) summary
    pfam00386
    Location:666 → 791
    C1q; C1q domain
    pfam12287
    Location:287 → 602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  39. NM_001385531.1 → NP_001372460.1  caprin-2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:665 → 790
    C1q; C1q domain
    pfam12287
    Location:287 → 601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  40. NM_001385532.1 → NP_001372461.1  caprin-2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:665 → 790
    C1q; C1q domain
    pfam12287
    Location:287 → 601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  41. NM_001385533.1 → NP_001372462.1  caprin-2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:665 → 790
    C1q; C1q domain
    pfam12287
    Location:287 → 601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  42. NM_001385534.1 → NP_001372463.1  caprin-2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:665 → 790
    C1q; C1q domain
    pfam12287
    Location:287 → 601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  43. NM_001385535.1 → NP_001372464.1  caprin-2 isoform 25

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (3) summary
    PTZ00121
    Location:240 → 488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539 → 749
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119 → 234
    Caprin-1_dimer; Caprin-1 dimerization domain

  44. NM_001385537.1 → NP_001372466.1  caprin-2 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:645 → 770
    C1q; C1q domain
    pfam12287
    Location:287 → 581
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  45. NM_001385538.1 → NP_001372467.1  caprin-2 isoform 27

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (3) summary
    PTZ00121
    Location:7 → 193
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:642 → 767
    C1q; C1q domain
    pfam12287
    Location:264 → 578
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  46. NM_001385539.1 → NP_001372468.1  caprin-2 isoform 28

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00449
    Location:80 → 421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:631 → 756
    C1q; C1q domain
    pfam12287
    Location:287 → 567
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  47. NM_001385540.1 → NP_001372469.1  caprin-2 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00449
    Location:80 → 421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:630 → 755
    C1q; C1q domain
    pfam12287
    Location:287 → 566
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  48. NM_001385541.1 → NP_001372470.1  caprin-2 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (3) summary
    PTZ00449
    Location:80 → 421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:630 → 755
    C1q; C1q domain
    pfam12287
    Location:287 → 566
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  49. NM_001385542.1 → NP_001372471.1  caprin-2 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00449
    Location:80 → 421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:610 → 735
    C1q; C1q domain
    pfam12287
    Location:287 → 546
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  50. NM_001385543.1 → NP_001372472.1  caprin-2 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (3) summary
    PTZ00449
    Location:57 → 398
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:608 → 733
    C1q; C1q domain
    pfam12287
    Location:264 → 544
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  51. NM_001385544.1 → NP_001372473.1  caprin-2 isoform 32

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00449
    Location:57 → 398
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:607 → 732
    C1q; C1q domain
    pfam12287
    Location:264 → 543
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  52. NM_001385545.1 → NP_001372474.1  caprin-2 isoform 33

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:7 → 236
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:581 → 706
    C1q; C1q domain
    pfam12287
    Location:287 → 517
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  53. NM_001385546.1 → NP_001372475.1  caprin-2 isoform 34

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:7 → 193
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:559 → 684
    C1q; C1q domain
    pfam12287
    Location:264 → 495
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  54. NM_001385547.1 → NP_001372476.1  caprin-2 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    H3BM22
    Conserved Domains (2) summary
    PTZ00121
    Location:7 → 236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287 → 602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  55. NM_001385548.1 → NP_001372477.1  caprin-2 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    H3BM22
    Conserved Domains (2) summary
    PTZ00121
    Location:7 → 236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287 → 602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  56. NM_001385549.1 → NP_001372478.1  caprin-2 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    H3BM22
    Conserved Domains (2) summary
    PTZ00121
    Location:7 → 236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287 → 602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  57. NM_001385550.1 → NP_001372479.1  caprin-2 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91671.1
    UniProtKB/TrEMBL
    A0A8I5KSM9, H3BM22
    Related
    ENSP00000510009.1, ENST00000690126.1
    Conserved Domains (2) summary
    PTZ00121
    Location:7 → 236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287 → 601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  58. NM_001385551.1 → NP_001372480.1  caprin-2 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91671.1
    UniProtKB/TrEMBL
    A0A8I5KSM9, H3BM22
    Conserved Domains (2) summary
    PTZ00121
    Location:7 → 236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287 → 601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  59. NM_001385552.1 → NP_001372481.1  caprin-2 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91671.1
    UniProtKB/TrEMBL
    A0A8I5KSM9, H3BM22
    Conserved Domains (2) summary
    PTZ00121
    Location:7 → 236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287 → 601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  60. NM_001385553.1 → NP_001372482.1  caprin-2 isoform 37

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    H3BM22
    Conserved Domains (2) summary
    PTZ00121
    Location:7 → 236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287 → 581
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  61. NM_001385554.1 → NP_001372483.1  caprin-2 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Consensus CDS
    CCDS91671.1
    UniProtKB/TrEMBL
    A0A8I5KSM9, H3BM22
    Conserved Domains (2) summary
    PTZ00121
    Location:7 → 236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287 → 601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  62. NM_001385557.1 → NP_001372486.1  caprin-2 isoform 38

    Status: REVIEWED

    Source sequence(s)
    AC010198
    UniProtKB/TrEMBL
    H3BM22
    Conserved Domains (2) summary
    PTZ00449
    Location:122 → 421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam12287
    Location:287 → 548
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  63. NM_001385559.1 → NP_001372488.1  caprin-2 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:645 → 770
    C1q; C1q domain
    pfam12287
    Location:287 → 581
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  64. NM_001416513.1 → NP_001403442.1  caprin-2 isoform 40

    Status: REVIEWED

    Source sequence(s)
    AC010198

  65. NM_023925.5 → NP_076414.2  caprin-2 isoform 2

    See identical proteins and their annotated locations for NP_076414.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2, also known as EEGL) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
    Source sequence(s)
    AC010198, AK021453, AL834212, AY074490, AY074491, BC025420, BQ010043, KF455635
    Consensus CDS
    CCDS8720.1
    UniProtKB/TrEMBL
    A0A8Q3SHV1
    Related
    ENSP00000298892.5, ENST00000298892.9
    Conserved Domains (3) summary
    pfam05483
    Location:88 → 510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam00386
    Location:949 → 1074
    C1q; C1q domain
    pfam12287
    Location:628 → 879
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  66. NM_032156.5 → NP_115532.3  caprin-2 isoform 3

    See identical proteins and their annotated locations for NP_115532.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the central coding region, and an alternate splice site in the 3' coding region that causes a frameshift, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC010198, BC007520, BC117672, BR000870, KF455635
    Consensus CDS
    CCDS41766.2
    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Related
    ENSP00000391479.1, ENST00000417045.5
    Conserved Domains (2) summary
    pfam05483
    Location:88 → 510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam12287
    Location:628 → 928
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

RNA

  1. NR_169636.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198

  2. NR_169638.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198

  3. NR_169639.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Related
    ENST00000690233.1

  4. NR_169640.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Related
    ENST00000548676.5

  5. NR_169641.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Related
    ENST00000695369.1

  6. NR_169643.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Related
    ENST00000695327.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    30709553..30754951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047429437.1 → XP_047285393.1  caprin-2 isoform X17

    UniProtKB/TrEMBL
    A0A8Q3WKC4
    Related
    ENSP00000511807.1, ENST00000695326.1

  2. XM_047429435.1 → XP_047285391.1  caprin-2 isoform X15

  3. XM_047429433.1 → XP_047285389.1  caprin-2 isoform X14

    UniProtKB/TrEMBL
    A0A8Q3SHS5
    Related
    ENSP00000511811.1, ENST00000695330.1

  4. XM_047429444.1 → XP_047285400.1  caprin-2 isoform X24

    Related
    ENSP00000415407.2, ENST00000433722.6

  5. XM_047429430.1 → XP_047285386.1  caprin-2 isoform X9

  6. XM_047429442.1 → XP_047285398.1  caprin-2 isoform X22

  7. XM_047429429.1 → XP_047285385.1  caprin-2 isoform X8

  8. XM_047429427.1 → XP_047285383.1  caprin-2 isoform X4

    UniProtKB/TrEMBL
    F5H5J8

  9. XM_047429439.1 → XP_047285395.1  caprin-2 isoform X19

  10. XM_047429438.1 → XP_047285394.1  caprin-2 isoform X18

  11. XM_047429434.1 → XP_047285390.1  caprin-2 isoform X14

    UniProtKB/TrEMBL
    A0A8Q3SHS5

  12. XM_047429428.1 → XP_047285384.1  caprin-2 isoform X7

  13. XM_047429441.1 → XP_047285397.1  caprin-2 isoform X21

  14. XM_017019854.2 → XP_016875343.1  caprin-2 isoform X6

    UniProtKB/TrEMBL
    A0A8Q3SHV1

  15. XM_006719144.4 → XP_006719207.1  caprin-2 isoform X5

    UniProtKB/TrEMBL
    A0A8Q3SHV1
    Conserved Domains (3) summary
    pfam05483
    Location:88 → 510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam00386
    Location:915 → 1040
    C1q; C1q domain
    pfam12287
    Location:628 → 845
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  16. XM_047429440.1 → XP_047285396.1  caprin-2 isoform X20

  17. XM_017019851.2 → XP_016875340.1  caprin-2 isoform X2

    UniProtKB/TrEMBL
    A0A8Q3WKF3

  18. XM_047429432.1 → XP_047285388.1  caprin-2 isoform X13

  19. XM_017019865.2 → XP_016875354.1  caprin-2 isoform X12

    UniProtKB/TrEMBL
    A0A8Q3WKE7

  20. XM_047429426.1 → XP_047285382.1  caprin-2 isoform X3

  21. XM_047429436.1 → XP_047285392.1  caprin-2 isoform X16

  22. XM_047429425.1 → XP_047285381.1  caprin-2 isoform X1

  23. XM_006719147.4 → XP_006719210.1  caprin-2 isoform X11

    UniProtKB/TrEMBL
    A0A8Q3WKE7
    Conserved Domains (2) summary
    pfam05483
    Location:88 → 510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam12287
    Location:628 → 908
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

  24. XM_047429431.1 → XP_047285387.1  caprin-2 isoform X10

  25. XM_047429443.1 → XP_047285399.1  caprin-2 isoform X23

    Related
    ENSP00000438010.1, ENST00000537108.5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    30584217..30698047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054373020.1 → XP_054228995.1  caprin-2 isoform X25

  2. XM_054373030.1 → XP_054229005.1  caprin-2 isoform X17

  3. XM_054373028.1 → XP_054229003.1  caprin-2 isoform X15

  4. XM_054373026.1 → XP_054229001.1  caprin-2 isoform X14

  5. XM_054373036.1 → XP_054229011.1  caprin-2 isoform X24

  6. XM_054373021.1 → XP_054228996.1  caprin-2 isoform X9

  7. XM_054373019.1 → XP_054228994.1  caprin-2 isoform X8

  8. XM_054373015.1 → XP_054228990.1  caprin-2 isoform X4

  9. XM_054373032.1 → XP_054229007.1  caprin-2 isoform X19

  10. XM_054373031.1 → XP_054229006.1  caprin-2 isoform X18

  11. XM_054373027.1 → XP_054229002.1  caprin-2 isoform X14

  12. XM_054373018.1 → XP_054228993.1  caprin-2 isoform X7

  13. XM_054373034.1 → XP_054229009.1  caprin-2 isoform X21

  14. XM_054373017.1 → XP_054228992.1  caprin-2 isoform X6

  15. XM_054373016.1 → XP_054228991.1  caprin-2 isoform X5

  16. XM_054373033.1 → XP_054229008.1  caprin-2 isoform X20

  17. XM_054373013.1 → XP_054228988.1  caprin-2 isoform X2

  18. XM_054373025.1 → XP_054229000.1  caprin-2 isoform X13

  19. XM_054373024.1 → XP_054228999.1  caprin-2 isoform X12

  20. XM_054373014.1 → XP_054228989.1  caprin-2 isoform X3

  21. XM_054373029.1 → XP_054229004.1  caprin-2 isoform X16

  22. XM_054373012.1 → XP_054228987.1  caprin-2 isoform X1

  23. XM_054373023.1 → XP_054228998.1  caprin-2 isoform X11

  24. XM_054373022.1 → XP_054228997.1  caprin-2 isoform X10

  25. XM_054373035.1 → XP_054229010.1  caprin-2 isoform X23

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6IMN6.1 GenPept UniProtKB/Swiss-Prot:Q6IMN6

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