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Bpifb2 BPI fold containing family B, member 2 [ Mus musculus (house mouse) ]

Gene ID: 66557, updated on 9-Dec-2024

Summary

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Official Symbol
Bpifb2provided by MGI
Official Full Name
BPI fold containing family B, member 2provided by MGI
Primary source
MGI:MGI:1913807
See related
Ensembl:ENSMUSG00000027481 AllianceGenome:MGI:1913807
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RYSR; Bpil1; LPLUNC2; 2310034L21Rik; 2310069A01Rik
Summary
Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Orthologous to human BPIFB2 (BPI fold containing family B member 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in testis adult (RPKM 3.4), mammary gland adult (RPKM 1.3) and 1 other tissue See more
Orthologs
human all
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Genomic context

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See Bpifb2 in Genome Data Viewer
Location:
2 H1; 2 75.99 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (153716925..153737190)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (153875045..153895270)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene EF-hand calcium binding domain 8 Neighboring gene translocase of outer mitochondrial membrane 20 homolog pseudogene Neighboring gene Sad1 and UNC84 domain containing 5 Neighboring gene BPI fold containing family B, member 6 Neighboring gene BPI fold containing family B, member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Phylogenetic and evolutionary analysis of the PLUNC gene family. Bingle CD, et al. Protein Sci, 2004 Feb. PMID 14739326, Free PMC Article
  2. Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Bingle CD, et al. Biochem Soc Trans, 2011 Aug. PMID 21787333, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC144836, MGC144837

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
BPI fold-containing family B member 2
Names
bactericidal/permeability-increasing protein-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025631.3 → NP_079907.2  BPI fold-containing family B member 2 precursor

    See identical proteins and their annotated locations for NP_079907.2

    Status: VALIDATED

    Source sequence(s)
    AK009776, AK010157, BC116681
    Consensus CDS
    CCDS16919.1
    UniProtKB/Swiss-Prot
    Q3TUY4, Q8BVZ0, Q8C1E1, Q8C1E2, Q9D713, Q9D744
    UniProtKB/TrEMBL
    Q14AS4, Q14AV3
    Related
    ENSMUSP00000028983.3, ENSMUST00000028983.3
    Conserved Domains (2) summary
    pfam01273
    Location:36 → 187
    LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain
    cl00188
    Location:258 → 458
    BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    153716925..153737190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162459.1 → XP_036018352.1  BPI fold-containing family B member 2 isoform X3

    Conserved Domains (1) summary
    pfam01273
    Location:36 → 187
    LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

  2. XM_017319185.1 → XP_017174674.1  BPI fold-containing family B member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q3TUY4, Q8BVZ0, Q8C1E1, Q8C1E2, Q9D713, Q9D744
    UniProtKB/TrEMBL
    Q14AS4, Q14AV3
    Conserved Domains (2) summary
    pfam01273
    Location:36 → 187
    LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain
    cl00188
    Location:258 → 458
    BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

  3. XM_006500007.1 → XP_006500070.1  BPI fold-containing family B member 2 isoform X2

    Conserved Domains (1) summary
    cl00188
    Location:46 → 246
    BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C1E1.1 GenPept UniProtKB/Swiss-Prot:Q8C1E1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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