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Tmed7 transmembrane p24 trafficking protein 7 [ Mus musculus (house mouse) ]

Gene ID: 66676, updated on 9-Dec-2024

Summary

Official Symbol
Tmed7provided by MGI
Official Full Name
transmembrane p24 trafficking protein 7provided by MGI
Primary source
MGI:MGI:1913926
See related
Ensembl:ENSMUSG00000033184 AllianceGenome:MGI:1913926
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TRAM; 3930401E15Rik; 5830493P14Rik
Summary
Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in embryo. Orthologous to several human genes including TMED7 (transmembrane p24 trafficking protein 7). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in adrenal adult (RPKM 75.2), ovary adult (RPKM 35.0) and 28 other tissues See more
Orthologs
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Genomic context

See Tmed7 in Genome Data Viewer
Location:
18 C; 18 24.65 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (46718995..46730602, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (46585928..46597535, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene TIR domain containing adaptor molecule 2 Neighboring gene RAD51 homolog c pseudogene Neighboring gene eukaryotic translation initiation factor 1A Neighboring gene predicted gene 3734

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
transmembrane emp24 domain-containing protein 7
Names
transmembrane emp24 protein transport domain containing 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025698.1NP_079974.1  transmembrane emp24 domain-containing protein 7 precursor

    Status: VALIDATED

    Source sequence(s)
    AK013936, AV225029, AV231886, AW544395, BB620206, CD565393, CN696073, CX219174
    Consensus CDS
    CCDS50283.1
    UniProtKB/TrEMBL
    D3YZZ5, E9Q7G1
    Related
    ENSMUSP00000120904.2, ENSMUST00000151189.2
    Conserved Domains (1) summary
    pfam01105
    Location:36213
    EMP24_GP25L; emp24/gp25L/p24 family/GOLD

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    46718995..46730602 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)